Protein Alignment CG5966 and Lipc

DIOPT Version :10

• Sequence 1: NP_572286.1
• Gene: CG5966 / 31532
• FlyBaseID: FBgn0029831
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001398717.1
• Gene: Lipc / 15450
• MGIID: 96216
• Length: 526
• Species: Mus musculus
• Alignment Length: 507
• Identity: 134/507 - (26%)
• Similarity: 210/507 - (41%)
• Gaps: 114/507 - (22%)

  Fly    86 RALDQPK-----YLDLND----------PESVQGMGMNPKGKIFLLVHGY--LESGEI------- 126
            :.|.:|:     :.|.||          ||::|..|.|....:.:::||:  .||..:
Mouse    42 KPLKKPETRFLLFQDENDRLGCRLRPQHPETLQECGFNSSQPLIMIIHGWSGSESATVGKDSDSD 106

  Fly   127 --------PWMWDMAKALLAHEPEGRASVVLIDWGGGASPPYVQAVANIRLVGAITAHVVHMLYE 183
                    .|:|.:..||.:.:.: ..:|.|:||...|...|..||.|.|:||...|.::..|.|
Mouse   107 YQVDGLLENWIWKIVSALKSRQSQ-PVNVGLVDWISLAYQHYTIAVQNTRIVGQDVAALLLWLEE 170

  Fly   184 ELRLPNLDNVHIIGHSLGAHLSGYAGYHLQHDFGLKPARITGLDPAAPLFTDTDPIVRLDKTDAH 248
            ..:. :...||:||:|||||:||:||..:  |...|..||||||||.|:|..|.|..||...||:
Mouse   171 SAKF-SRSKVHLIGYSLGAHVSGFAGSSM--DGKNKIGRITGLDPAGPMFEGTSPNERLSPDDAN 232

  Fly   249 FVDIVHTDANPLMKGGLGINMRLGHVDFFPNGGFDNPGCN--KKFQDVVKKKTLFLTMQEFLGCN 311
            |||.:||.....|...:||...:.|.||:||||...|||:  :.::.:.:.....:|  :.:.|.
Mouse   233 FVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAIT--QTIKCA 295

  Fly   312 HIRSQQYFTESI-GSQCPFLGITCDSFESFKDTKCTSCEEPGHTCLRMGYHSQEDYQEQVDLGQL 375
            |.||...|.:|: .|....:|..|....||....|.||::  ..|..:||..::|
Mouse   296 HERSVHLFIDSLQHSDLQSIGFQCSDMGSFSQGLCLSCKK--GRCNTLGYDIRKD---------- 348

  Fly   376 QQGDSPGVFYLWTGDSKPFCRLHYRITVRVSGHDES--------TLHG--GEVGILSIQLHDALV 430
            :.|.|..:| |.|....||...||:..::.....|.        :|.|  .|:..:.|.|.:.:.
Mouse   349 RSGKSKRLF-LITRAQSPFKVYHYQFKIQFINQIEKPVEPTFTMSLLGTKEEIKRIPITLGEGIT 412

  Fly   431 KKAGKNERAATEMMKFSQKAMYFEPGYEYKALVAGRNLREPEYATVNWEYPTNILNPLTWRILSA 495
                            |.|...|       .:...:::.|.......||      |...|
Mouse   413 ----------------SNKTYSF-------LITLDKDIGELILLKFKWE------NSAVW----- 443

  Fly   496 PRIY--LEYILIEAMESSDLYLKLCPQHEGAIL-----TGAENVLRSSYCKD 540
            ..::  ::.|::..:|         |.|.|.||     ...|...|.::|.:
Mouse   444 ANVWNTVQTIMLWGIE---------PHHSGLILKTIWVKAGETQQRMTFCPE 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5966	NP_572286.1	Pancreat_lipase_like	76..390	CDD:238363	106/338 (31%)
Lipc	NP_001398717.1	Lipase	18..366	CDD:395099	106/342 (31%)
		PLAT_LPL	369..504	CDD:238856	26/161 (16%)