Protein Alignment mof and KAT8

DIOPT Version :10

• Sequence 1: NP_511051.1
• Gene: mof / 31518
• FlyBaseID: FBgn0014340
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_892003.2
• Gene: KAT8 / 84148
• HGNCID: 17933
• Length: 467
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 234/438 - (53%)
• Similarity: 310/438 - (70%)
• Gaps: 49/438 - (11%)

  Fly   366 GDPLMQKIDISENPDKIYFIRREDGTVHRGQVLQSRTTENAAAPDEYYVHYVGLNRRLDGWVGRH 430
            |:|.: .::|.|.    |..||.|.|.|..:|:|||..:.... :|:||||||.|||||.||.::
Human    49 GEPEV-TVEIGET----YLCRRPDSTWHSAEVIQSRVNDQEGR-EEFYVHYVGFNRRLDEWVDKN 107

  Fly   431 RISDNADDLGGITVLPAPPLAPDQPSTSREMLAQQAAAAAAASSERQKRAANKDYYLSYCENSRY 495
            |::                            |.:....|...:||:         |||    ...
Human   108 RLA----------------------------LTKTVKDAVQKNSEK---------YLS----ELA 131

  Fly   496 DYSDRKMTRYQKRRYDEINHVQKSHAELTATQAALEKEHESITKIKYIDKLQFGNYEIDTWYFSP 560
            :..:||:||.|||::||||||||::||:..|.||||||||:|||:||:||:..||||||.|||||
Human   132 EQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIGNYEIDAWYFSP 196

  Fly   561 FPEEYGKARTLYVCEYCLKYMRFRSSYAYHLHECDRRRPPGREIYRKGNISIYEVNGKEESLYCQ 625
            |||:|||...|::||||||||::..||.:||.:|..|:|||:|||||.|||:|||:||:..:|||
Human   197 FPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQ 261

  Fly   626 LLCLMAKLFLDHKVLYFDMDPFLFYILCETDKEGSHIVGYFSKEKKSLENYNVACILVLPPHQRK 690
            .|||:||||||||.||||::||:||||.|.|::|:||||||||||:|.:..||||||.|||:||:
Human   262 NLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRR 326

  Fly   691 GFGKLLIAFSYELSRKEGVIGSPEKPLSDLGRLSYRSYWAYTLLELMKTRCAPEQITIKELSEMS 755
            |:||.|||||||||:.|..:|||||||||||:|||||||::.|||::  |.....::||:||:|:
Human   327 GYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEIL--RDFRGTLSIKDLSQMT 389

  Fly   756 GITHDDIIYTLQSMKMIKYWKGQNVICVTSKTIQDHLQLPQFKQPKLT 803
            .||.:|||.||||:.|:||||||:|||||.|.:::||:..|:|:|.:|
Human   390 SITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPIT 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mof	NP_511051.1	PLN00104	387..813	CDD:215056	228/417 (55%)
KAT8	NP_892003.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53		2/3 (67%)
		PLN00104	15..429	CDD:215056	230/428 (54%)
		Nuclear localization signal. /evidence=ECO:0000269|PubMed:28991411	140..149		5/8 (63%)