Protein Alignment CG12729 and PSMF1

DIOPT Version :10

• Sequence 1: NP_572271.1
• Gene: CG12729 / 31515
• FlyBaseID: FBgn0029816
• Length: 233
• Species: Drosophila melanogaster
• Sequence 2: NP_006805.2
• Gene: PSMF1 / 9491
• HGNCID: 9571
• Length: 271
• Species: Homo sapiens
• Alignment Length: 187
• Identity: 38/187 - (20%)
• Similarity: 75/187 - (40%)
• Gaps: 22/187 - (11%)

  Fly    44 QLLLHSIQSHIRKKSDLLIAVTHF-LITKEYRLRCAINYSASDGRQLAGGCGTVCEQLPDHWNRD 107
            ::|..|....|..:.|.|:...|: ::|..|       :....|.| .|......|.||..||.:
Human     5 EVLFASAAPAITCRQDALVCFLHWEVVTHGY-------FGLGVGDQ-PGPNDKKSELLPAGWNNN 61

  Fly   108 ADRYTL--NYTDGLAGQYILMAKLSRRDLVISLQNSTSKRMAIVCLQPEHLVNSTCKSSMDKCIP 170
            .|.|.|  .|.|| :.:.::.|......:::::....|:::|.:.|..:..:::.......:...
Human    62 KDLYVLRYEYKDG-SRKLLVKAITVESSMILNVLEYGSQQVADLTLNLDDYIDAEHLGDFHRTYK 125

  Fly   171 RLDKFIKRLRAELVDPA--------VRGTKRLAEIGPAFNRKIWKRELPVRNSGTSR 219
            ..::...|:.:.::.|.        |....|  |..||..|::....:|..:..|||
Human   126 NSEELRSRIVSGIITPIHEQWEKANVSSPHR--EFPPATAREVDPLRIPPHHPHTSR 180

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12729	NP_572271.1	PI31_Prot_N	50..193	CDD:463296	27/153 (18%)
PSMF1	NP_006805.2	Important for homodimerization and interaction with FBXO7. /evidence=ECO:0000269|PubMed:18495667	2..150		28/153 (18%)
		PI31_Prot_N	11..148	CDD:463296	26/145 (18%)
		PI31_Prot_C	182..248	CDD:430086
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	222..271