Protein Alignment Prosbeta2R1 and PSMB10

DIOPT Version :10

• Sequence 1: NP_572267.1
• Gene: Prosbeta2R1 / 31511
• FlyBaseID: FBgn0029812
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_002792.1
• Gene: PSMB10 / 5699
• HGNCID: 9538
• Length: 273
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 129/263 - (49%)
• Similarity: 187/263 - (71%)
• Gaps: 4/263 - (1%)

  Fly    20 RSGFNFINCRRNAEL--LSKGYEPPKAIKTGTSIVGIIYKDGVILGADTRATEGPIVSDKNCSKI 82
            |.||:|.||:|||.|  :..|.:.|.|.||||:|.|::::||||||||||||...:|:||:|.||
Human     9 RGGFSFENCQRNASLERVLPGLKVPHARKTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKI 73

  Fly    83 HHLQDHIYCCGAGTAADTEMITLTTSAELDLHRLNTERRVPVVCASMMLRRTLFRYQGHIGAALV 147
            |.:...|||||||.|||.||.|...:::::||.|:|.|...|...:.:||:||||||||:||:|:
Human    74 HFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLI 138

  Fly   148 MGGVDTTGPQLYCIYPCGSNDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQGKQLVREAISAGVF 212
            :||||.||||||.::|.||..::|:.|:|||..||::|||..::|::.||..:.|:.||::||:.
Human   139 VGGVDLTGPQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGIL 203

  Fly   213 NDLGSGSNIDLCVITAKGAVYLRTDTIASEKGERLGKYGIKPNSTMVTSISV--LSLQVTDERIY 275
            .|||||.|:|.||||..||..|||.:..:|..:|.|:|...|.:|.|.:.:|  |:|::.:|.:.
Human   204 GDLGSGGNVDACVITKTGAKLLRTLSSPTEPVKRSGRYHFVPGTTAVLTQTVKPLTLELVEETVQ 268

  Fly   276 AVD 278
            |::
Human   269 AME 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2R1	NP_572267.1	proteasome_beta_type_7	49..236	CDD:239732	99/186 (53%)
		Pr_beta_C	240..274	CDD:463597	11/35 (31%)
PSMB10	NP_002792.1	proteasome_beta_type_7	40..227	CDD:239732	99/186 (53%)
		Pr_beta_C	231..267	CDD:463597	11/35 (31%)