Protein Alignment Prosbeta2R1 and PSMB5

DIOPT Version :10

• Sequence 1: NP_572267.1
• Gene: Prosbeta2R1 / 31511
• FlyBaseID: FBgn0029812
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_002788.1
• Gene: PSMB5 / 5693
• HGNCID: 9542
• Length: 263
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 64/235 - (27%)
• Similarity: 112/235 - (47%)
• Gaps: 15/235 - (6%)

  Fly    14 ADFVGLRSGFNFINCRRNAELLSKGY----EPPKAIKTGTSIVGIIYKDGVILGADTRATEGPIV 74
            ||.:.|..|    :......|.:.|:    ||...:..||:.:...::.|||:.||:|||.|..:
Human    25 ADLLDLGPG----SLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYI 85

  Fly    75 SDKNCSKIHHLQDHIYCCGAGTAADTEMITLTTSAELDLHRLNTERRVPVVCASMMLRRTLFRYQ 139
            :.:...|:..:..::....||.|||........:.:..::.|..:.|:.|..||.:|...:::|:
Human    86 ASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYK 150

  Fly   140 GHIGAALVMG----GVDTTGPQLYCIYPCGSNDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQGK 200
               |..|.||    |.|..||.||.:...|:.......::|||::.|..|::.|:..||::||..
Human   151 ---GMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAY 212

  Fly   201 QLVREAISAGVFNDLGSGSNIDLCVITAKGAVYLRTDTIA 240
            .|.|.||....:.|..||..::|..:...|.:.:.:|.:|
Human   213 DLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVA 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2R1	NP_572267.1	proteasome_beta_type_7	49..236	CDD:239732	53/190 (28%)
		Pr_beta_C	240..274	CDD:463597	1/1 (100%)
PSMB5	NP_002788.1	proteasome_beta_type_5	60..247	CDD:239730	53/189 (28%)