Protein Alignment Prosbeta2R1 and PSMA8

DIOPT Version :10

• Sequence 1: NP_572267.1
• Gene: Prosbeta2R1 / 31511
• FlyBaseID: FBgn0029812
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_653263.2
• Gene: PSMA8 / 143471
• HGNCID: 22985
• Length: 256
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 56/226 - (24%)
• Similarity: 90/226 - (39%)
• Gaps: 28/226 - (12%)

  Fly    43 KAIKTGTSIVGIIYKDGVILGADTRATEGPIVSDKNCSKIHHLQDHIYCCGA--------GTAAD 99
            :|:|.|::.|||...:.|:||.:.::. ..:..::...||..|.||:  |.|        |..||
Human    26 EAVKKGSTAVGIRGTNIVVLGVEKKSV-AKLQDERTVRKICALDDHV--CMAFAVLTIFIGLTAD 87

  Fly   100 TEMITLTTSAELDLHRLNTERRVPVVCASMMLRRTLFRYQGHIG------AALVMGGVDTTGPQL 158
            ..::......|...|:|..|..|.|...:..:.....:|....|      :||::|..|....:|
Human    88 ARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDDDGISRL 152

  Fly   159 YCIYPCGSNDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQGKQLVREAISAGVFNDLGSGSNIDL 223
            |...|.|:.......|:|.........||..:..|. :....:.::.||.|.:......|.||:|
Human   153 YQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDA-IASDSEAIKLAIKALLEVVQSGGKNIEL 216

  Fly   224 CVI---------TAKGAVYLRTDTIASEKGE 245
            .:|         :|| .|.|....|..||.|
Human   217 AIIRRNQPLKMFSAK-EVELYVTEIEKEKEE 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2R1	NP_572267.1	proteasome_beta_type_7	49..236	CDD:239732	49/209 (23%)
		Pr_beta_C	240..274	CDD:463597	3/6 (50%)
PSMA8	NP_653263.2	proteasome_alpha_type_7	5..219	CDD:239724	47/196 (24%)