Protein Alignment CG42699 and cep162

DIOPT Version :10

• Sequence 1: NP_572263.2
• Gene: CG42699 / 31507
• FlyBaseID: FBgn0261610
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: XP_012818979.2
• Gene: cep162 / 100379880
• XenbaseID: XB-GENE-5961769
• Length: 1398
• Species: Xenopus tropicalis
• Alignment Length: 1068
• Identity: 214/1068 - (20%)
• Similarity: 416/1068 - (38%)
• Gaps: 311/1068 - (29%)

  Fly    22 NSSSIIEFLAKEQDCGGILNDPDPESIFQEV--SRLSDST-----DMRSVDELLQEAERLIQQQL 79
            :|.|.|:|          :|..||.::...|  .||....     |.|:..:||.     :...:
 Frog   401 SSDSEIQF----------INSRDPLTLKNSVGEERLGHQAYTIHQDERNSHDLLN-----LDHNV 450

  Fly    80 RLGGIVPKLDASGPPAPT------KTLGEEAATGGDGSSSSPQSSPHSSIRLNTRYTHRIEHSPA 138
            .....||.|..:...:||      :.|.....:.|.|.||:...:|..:::.|:        ...
 Frog   451 NTFANVPGLKLNKDKSPTSLPKRPQNLYAHVRSSGYGKSSTRLKAPALALKFNS--------GEL 507

  Fly   139 PLAPKTVAVNGRVRPRSGS----------------KSSASPTSVQTPLESSNGCGFAA------- 180
            |:..|..:.|   |...|:                |.|.:..:||...:|.....|..
 Frog   508 PVERKDTSPN---RKHKGALSSTRILRFAGTETIPKQSRNDYTVQHKEKSVLQMDFDKTETVLQH 569

  Fly   181 -FVDNLPSASVISEES-TPKDMDMENHTAAMAKLQLQQLQDNTDDDED----TMEEITEAEVDAP 239
             ..|:..|||....:| .|:.::|.:....|. |:||.::...:.|:.    ..||..:.|.:
 Frog   570 DMTDSFRSASGFHVDSNAPQSLNMSDAELNMF-LKLQNIEQKLNSDQTHSNILREEFLKKEEE-- 631

  Fly   240 IFSRAED--TGKEVRSPPERQFKSQGRSYIQPSQPIRPMASYSEKAVG----SSPKRMVSTLTSP 298
            ...:.||  |..||.....:|     .:||.    :..:.:..:|::.    ..||..|:  ...
 Frog   632 FLEKIEDLKTKYEVELQQHKQ-----ENYIL----LTKLHAMEDKSINKVNLGDPKDPVT--DEK 685

  Fly   299 IEQIASSVSRE----HALKLEIEQLQERLKDTE-------------------------ERLASV- 333
            |:||...:..:    |..:.|.|:|.:::|:.:                         |:|:.|
 Frog   686 IQQIRKEIEEQEKLLHGYQQENERLYQQVKELQIRNKQNEELMFQENQSLKANLLSLREQLSKVT 750

  Fly   334 ----RLQSDS--------------LSQTQRALREHN-----SRLQEESEMLKLDVQHLNECANVL 375
                |.|.:|              |...|:  ||.|     ||.:::.:.|::|:..:.:..:.:
 Frog   751 ISHQRPQDNSEKCNSQSFTDLLVELRTVQK--REANLLDEISRQKQDKQALEVDLMQMRKERDNV 813

  Fly   376 RSELQAARRDRGEALQMQRS-----------------------------LRDELEE--------- 402
            ::.|.....|:...::|...                             |||..|:
 Frog   814 KTLLSHTSGDKSYEMKMMEETYKQEINVLNKKLKWFAENQELLDKDANRLRDAYEQIEILKMQVE 878

  Fly   403 ------ANQERRRTGEGKEK--DSRVIQDLQRQCREMERILMRKHPDSVSALIVASKSSGMCPLN 459
                  .||..::....||:  |::.||||:||.:|||.|:.|:||:|:.|||.|:.::..|...
 Frog   879 KLKNETGNQSVQQQKRAKERAADAKRIQDLERQVKEMEGIIKRRHPNSIPALIFAAAAAPECDDK 943

  Fly   460 DQENVNSRKLLEQRIAQLESDAKEQDRKAQQILANVQARFNSVQAKYETHIADLETQVLSLQEIN 524
            |....|:...||:|:.:||:|.:.:|.::::.|..::.:|..|:.:||:.|.:|| ::|:.:.:|
 Frog   944 DSAKKNTIAFLERRVKKLETDLESKDDESKKSLRTMEQQFQKVKIQYESRIKELE-ELLTHKLMN 1007

  Fly   525 ---------TKLNEQIESQV-------RTLDRYMQKRADRYYNNCTQTEPLEEDDVSVGGGVNHG 573
                     ||. ::.|.::       :|..:.:|::.|.:..   :...||:::
 Frog  1008 PPQKPFDNSTKA-QKFEDELLICKETRQTTIQNLQRQIDLHRK---KNLVLEKNE---------- 1058

  Fly   574 RATPVSSNTMGTQTQAANGTRDHST-NTIGCPSPALVCQQ---QHLHQAHGHLHPHAPSASSSTS 634
            |....:.:.:||:.:      :||. :.:...|..|:.::   |.|.:....|........|.
 Frog  1059 RKKEANLSDIGTKVE------EHSNKDLLAKISQELIAKRIEIQDLTKTVERLQKERMIMLSV-- 1115

  Fly   635 STANSTPNTSRPNSKQSGGQRRSPLVTAGPSKLPISQSDSTLSLLSHGG-------GGSKEEAQL 692
                                 ::||:.|...|  .||:.:.:|.|....       .|:.:|.|.
 Frog  1116 ---------------------KNPLIKAADKK--SSQARTDISALGKRSIRDNMNFPGTLDEKQY 1157

  Fly   693 -LSSVRSMRV-DLAIKNKAM----QRLTRELDECKKTIRKLQRDKEGS-----GSGSQTGSKLDL 746
             ..:...:.: |...:|.|:    :||:.:::|.|:|.:.|....|.:     ..||:..|.|.|
 Frog  1158 HPGTFADIHISDAQAENTALKCEVERLSLKINEQKETFQTLLSQAENTIKRLKEEGSEQASALKL 1222

  Fly   747 RSQASGGAMQQRRSSGYDHHHHSDHIPA---------ATESQALKEAQNKYRLLEADYKTLHDKR 802
                    :.|:........|..||..:         :|:...:|..|.:.:.|:.|.::|...|
 Frog  1223 --------LHQKEVEKLICQHAIDHSSSKVAELSSKTSTQEILIKHLQTQVKELQKDRESLSIYR 1279

  Fly   803 LQDLKTLQSAHERELASCNETVRILQQRLNEREEALTTQKRRKVPVDYYALKAKVSLLERRHSER 867
            ::: :|||          .|..::|:: |.|.:|..:.:.:     |:.||:.|:..:|:||.:|
 Frog  1280 IRE-ETLQ----------KEVAKLLEE-LKEAKERYSPEMK-----DFLALENKIKYMEKRHLQR 1327

  Fly   868 EERLHMLVEALSKGRLNGALEDLMQENN 895
            |:.|..:::...    :.|.::.:||.:
 Frog  1328 EQELQQIIQQTH----HVAADEQIQETD 1351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42699	NP_572263.2	Smc	<311..>562	CDD:440809	77/361 (21%)
cep162	XP_012818979.2	SMC_prok_B	684..1375	CDD:274008	150/745 (20%)