DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3097 and Cpa3

DIOPT Version :9

Sequence 1:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_062173.1	Gene:	Cpa3 / 54242	RGDID:	2390	Length:	417	Species:	Rattus norvegicus

Alignment Length:	442	Identity:	134/442 - (30%)
Similarity:	224/442 - (50%)	Gaps:	40/442 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LQLLLLVAAVAASLANELPSNLTLLDANEIPQRYDEAQLWRIYNISEAMQKRVPVGQMLEQKFGG 72
            ::..||:..:.::||             ..|.::|..:::|:....|   |:..:.:.|.|....
  Rat     1 MRSFLLMGVIYSTLA-------------IAPVQFDREKVFRVKLQDE---KQASILKNLTQTIEL 49

  Fly    73 NIWKEN-------SKFLDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEELLEGIQSSSFG 130
            :.|..:       :..:|..:...:.:..:|.|..|::|.:||.:::|..||::.
  Rat    50 DFWYPDAIHDIAVNMTVDFRVTEKESQTIQSTLEQHKMDYEILINDLQEEIDKQF---------- 104

  Fly   131 HGRRTKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVLRISENPREN 195
             ..:.:.|.|.|  :..|:|...|.|:..::..|.|.:|....||.|.|...|.||:|.....|.
  Rat   105 -DVKEEIAGRHS--YAKYNDWNKIVSWTEKMVEKHPEMVSRIKIGSTVEDNPLYVLKIGRKDGER 166

  Fly   196 KKVWIDGGIHAREWISPATVTFILYQLMSDWENQPAHIR---GLTWYIMPVMNPDGYEYSRTTNR 257
            |.:::|.|||||||:|||...:.:||....:.......:   .:.:|::||.|.|||.:|.|.:|
  Rat   167 KAIFMDCGIHAREWVSPAFCQWFVYQAAKSYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTKDR 231

  Fly   258 LWRKNRSPSRRAQCSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAVAEFLAKRKYN 322
            :||||||.:..:.|.|.|||||||:.|:...::.|||...|||.||.||:||:||..|:.....:
  Rat   232 MWRKNRSKNPNSTCIGTDLNRNFDVSWDSSPNTDNPCLSVYRGPAPESEKETKAVTNFIRSHLNS 296

  Fly   323 LESYLTFHSYGQMIVYPWAYKAVKVKDASVLQRVSSLAAERILQKTGTSYRAAVTHEVLGIAGGG 387
            :::|:|||||.||:::|:.|......:...|.:|:.:|.:.:..:..|.|........:....|.
  Rat   297 IKAYITFHSYSQMLLFPYGYTIKLPPNHQDLLKVARIATDVLSSRYETRYIYGPIASTIYKTSGS 361

  Fly   388 SDDWSRAALGVKYVYTIELRDRGAYGFVLPPRFIKDTALEGWTVVETVAQAI 439
            |.||: ..||:|:.:..||||:|..||:||...||.|..|....|:.:|:.|
  Rat   362 SLDWA-YDLGIKHTFAFELRDKGKSGFLLPESRIKPTCKETMLSVKFIAKYI 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416	12/60 (20%)
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	108/293 (37%)
Cpa3	NP_062173.1	Propep_M14	28..102	CDD:280416	15/76 (20%)
Cpa3	NP_062173.1	Peptidase_M14_like	114..413	CDD:299699	110/302 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351593
Domainoid	1	1.000	222	1.000	Domainoid score	I2495
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8927
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.750