DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15773 and CG15170

DIOPT Version :9

Sequence 1:	NP_572251.1	Gene:	CG15773 / 31494	FlyBaseID:	FBgn0029795	Length:	478	Species:	Drosophila melanogaster
Sequence 2:	NP_609927.1	Gene:	CG15170 / 35160	FlyBaseID:	FBgn0032733	Length:	561	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	144/458 - (31%)
Similarity:	199/458 - (43%)	Gaps:	71/458 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LIIMGLAIVDS-----LECYACDSAEDSECATRPGQ--QLEVEECQQTGDECVTSISAGLTRRGC 77
            |:::.|.::.|     :.||.|||....||:...|:  .|..:|| .|...|..||...:|.|||
  Fly    15 LLLLFLVLLRSDRCFGIVCYHCDSIALPECSQTLGEVGVLPYKEC-ATELTCAMSIVDSITYRGC 78

  Fly    78 LARLYPNGYCAAPCDRCNTSLCNRHVYPADRLRCYQCSGSDCIDV-ASRPQYLLPCPVYQEDDRC 141
            .|.....|  |.....|:|:|||..|||..||:|:.|:|.:|:.. ||:|:   ||..:.|:|:|
  Fly    79 GAETPIIG--ATYSKTCSTNLCNAGVYPPGRLKCHHCAGQECVAAPASKPK---PCRYHLEEDQC 138

  Fly   142 YTNVVHLSNTLRGC----EHTNLPTTCPHVCLKCNYNGCNAEKTVTELRCLQCTHNRLAPNPDCL 202
            ||:|:..|:..|||    .|| |.|:..    .|..||||.|:......|..|..   |....|.
  Fly   139 YTDVISSSDAYRGCTSEQNHT-LSTSAQ----LCEINGCNEEQGAWTQVCATCDS---AIGRGCK 195

  Fly   203 RDQDPPAAVAEDQPKCSLSNSTVTHCVNKVMYGHREN--CFSYRNTQTEVLQRGCSTAMGFYPTG 265
            .|     ....:..:|::  |....|...|:.|.:|:  |||:|.....|  |||||.:   ||.
  Fly   196 ID-----LFQVNTGRCNV--SLYEECQQDVLLGEQEDKYCFSFRRLSRVV--RGCSTKI---PTD 248

  Fly   266 ------ELTECH-GEFCNADC-QDIVCAACNSTANPGCRAG-RNLPTEKC-AAGTTACYSCEQDT 320
                  :|.:|: .:.|||.| ....|..|||.....||.. ..:....| :|..::|:|||..
  Fly   249 LEPYVEQLEKCNTSDHCNAGCITQQKCFTCNSVDQELCRTNITAIANSTCSSAEASSCFSCEYS- 312

  Fly   321 LVTHFPFIIPNTFLRRGCADADFAPAALGESCQLCRDADGCNRYSVRSCYRCNAQDQDSDCAAMD 385
                      |..::|||......|..  ..|..|.:..|||......||:|:.....:.||..:
  Fly   313 ----------NWSIQRGCGAPPENPQI--TKCYECDEGAGCNSKDFTRCYQCSTDQAGAGCANWE 365

  Fly   386 LPTTMTTSNCSSPTELCVSTVVSRLDGIYTVRGCEGQVPEC-SANDPYCVRCNGSLCNDA----P 445
            .|..:....|..|...||  ||| .:...|.|||:.....| |||...|..|.||.||..    .
  Fly   366 SPGEIYIEECDEPAAPCV--VVS-FNNATTARGCQKSDFSCASANVASCRLCEGSFCNKGSFPEE 427

  Fly   446 TLW 448
            .||
  Fly   428 RLW 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15773	NP_572251.1	DUF753	36..155	CDD:283175	47/121 (39%)
CG15773	NP_572251.1	DUF753	287..438	CDD:283175	44/153 (29%)
CG15170	NP_609927.1	DUF753	35..166	CDD:283175	53/141 (38%)
		DUF753	278..416	CDD:283175	44/153 (29%)
		DUF753	351..506	CDD:283175	27/83 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455200
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D18141at33208
OrthoFinder	1	1.000	-	-		FOG0016902
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21721
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950