DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx27 and snx-14

DIOPT Version :9

Sequence 1:	NP_727023.1	Gene:	Snx27 / 31493	FlyBaseID:	FBgn0052758	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_496844.3	Gene:	snx-14 / 174997	WormBaseID:	WBGene00013011	Length:	971	Species:	Caenorhabditis elegans

Alignment Length:	228	Identity:	52/228 - (22%)
Similarity:	82/228 - (35%)	Gaps:	66/228 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 LTVISVTQQEADRLEPQEDQSG----YSYI-----------DYSDKRSLPIS---IPD------- 174
            ||.:|..::|...:|..|.|.|    .||:           |..::||.|..   ||.
Worm   519 LTSVSDEEKEEAGVETPESQGGSSTASSYVNIAAPSIDVIEDVEEERSEPAEEAPIPKTTGLVID 583

  Fly   175 -----------------YGIVNRNGERYI-VFNI---------HMAGRQLCSRRYREFANLHSLL 212
                             .|:.::..:|.| ||.|         |...|....|.:.||..|.|.|
Worm   584 SEPPINLNCWKVNVAQVNGLRDKISDRVIFVFIIEVERPDAKPHETQRWSIHRSFNEFYVLESKL 648

  Fly   213 RKEFSG--FNFPKLPGKWPFQLSEQQ-LDTRRRGLEQYLEKVCAVRVIAESDAVQDFLTDTE--- 271
             .||.|  ..|..||.:..|...::. ::..|.....:|..:...|::..|:.:..||:..|
Worm   649 -NEFHGDSLRFSPLPTRKTFVTRDKPFMEQHRLIFSTFLSTLSKQRILNRSELLLAFLSSNEEFR 712

  Fly   272 DDISASPVD----IKVMLPDHEVSTVSVKKSSN 300
            |.:|...::    :|..||.   ..|:.:|..|
Worm   713 DTLSLGDLNPWKVVKKTLPG---KLVNREKGQN 742

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx27	NP_727023.1	PDZ_signaling	46..138	CDD:238492	2/2 (100%)
		PX_SNX27	165..270	CDD:132796	32/144 (22%)
		UBQ	278..363	CDD:294102	6/27 (22%)
		FERM-like_C_SNX27	428..528	CDD:270146
snx-14	NP_496844.3	PXA	112..314	CDD:383027
		RGS	352..475	CDD:214613
		PX_SNX14	591..708	CDD:132787	27/117 (23%)
		Nexin_C	856..941	CDD:370015
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1370
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030