Protein Alignment CG33080 and MYORG

DIOPT Version :10

• Sequence 1: NP_788858.1
• Gene: CG33080 / 31491
• FlyBaseID: FBgn0053080
• Length: 925
• Species: Drosophila melanogaster
• Sequence 2: NP_065753.2
• Gene: MYORG / 57462
• HGNCID: 19918
• Length: 714
• Species: Homo sapiens
• Alignment Length: 758
• Identity: 198/758 - (26%)
• Similarity: 325/758 - (42%)
• Gaps: 123/758 - (16%)

  Fly   229 REKMQAFPQLIR----------------------------KKKRETKDYK--IKIFVIIMFFIII 263
            :||.||:|:..|                            .|.:.:||.|  :...|:.:..::.
Human     6 QEKSQAYPRRRRPGCYAYRQNPEAIAAAAMYTFLPDNFSPAKPKPSKDLKPLLGSAVLGLLLVLA 70

  Fly   264 FLIGYAYVAYHQQVLTRSYFQ---------KIKFNSHDRIFRILSHE---DKEVIS---GQLGVT 313
            .::.:.|.:...:...|...:         .|:....:::||:....   |.:..|   ..||.:
Human    71 AVVAWCYYSVSLRKAERLRAELLDLKAGGFSIRNQKGEQVFRLAFRSGALDLDSCSRDGALLGCS 135

  Fly   314 LGFDTAPFHCLEEQRRSDGSVCIEWNGVARLHLNFEDKGVFRCYTLQWQALTPGLLPTDCYELKR 378
            |..|..|.|...:..|                    .|....||.::|:...||........|..
Human   136 LTADGLPLHFFIQTVR--------------------PKDTVMCYRVRWEEAAPGRAVEHAMFLGD 180

  Fly   379 DNGLWFGGGVTKGQEWSLSY-ANFDFAPYASGD--SKIHQFGNGVKRYFINSIGVAMQVSEKTPL 440
            ....|:||...:.|.|.:.. ...:..|:.:.|  |....||..::||:::|...|::|::..|.
Human   181 AAAHWYGGAEMRTQHWPIRLDGQQEPQPFVTSDVYSSDAAFGGILERYWLSSRAAAIKVNDSVPF 245

  Fly   441 QLGVNRTENRFCLRAANDEFTFVNHLTP---------LPQLDYRICTTEDMRSLHMLMTQQSLWD 496
            .||.|.||....|:|.       .|.||         .|:|.||:|...|:.|:|..|.::..
Human   246 HLGWNSTERSLRLQAR-------YHDTPYKPPAGRAAAPELSYRVCVGSDVTSIHKYMVRRYF-- 301

  Fly   497 GLKEQEFKV-LHSLLEEPVW--------RIPHTELPESLNESAICDYSESAIAMGLGHIVINEFW 552
               .:..:| ......:|:|        .:...::.....:..:..::.|       |:.|::.:
Human   302 ---NKPSRVPAPEAFRDPIWSTWALYGRAVDQDKVLRFAQQIRLHHFNSS-------HLEIDDMY 356

  Fly   553 QENIGDFTVDKARFPTLKDTIDVLHRRGFKVVLTIQPFISTDSANFKDAVKRKLLIYERHSERSI 617
            ....|||..|:.:||...|....|...||:|.|.:.||::.:|:.|.:.|:|:|.:  |.....:
Human   357 TPAYGDFDFDEVKFPNASDMFRRLRDAGFRVTLWVHPFVNYNSSRFGEGVERELFV--REPTGRL 419

  Fly   618 PALTRYKSSSSAGVLDITNNASVPWLLEKLQRLKEEYGVQSFYLDLGTGYNLPHYYQCRQTLDNP 682
            |||.|:.:...| |||.|:..:..|....|:||:..|.|.||..|.|....||..:...:.|.:|
Human   420 PALVRWWNGIGA-VLDFTHPKARDWFQGHLRRLRSRYSVASFKFDAGEVSYLPRDFSTYRPLPDP 483

  Fly   683 DTYARLFT-ASLEGAGLMAVSTASVVPKPPTFLSTPPANATWE---GLRETLGAVLNYGVIGYPF 743
            ..::|.:| .:|....|..|...........|......::.|.   |||..:.|||...::||||
Human   484 SVWSRRYTEMALPFFSLAEVRVGYQSQNISCFFRLVDRDSVWGYDLGLRSLIPAVLTVSMLGYPF 548

  Fly   744 VLPGVIGGDYLLQRPLSKMVSFYSLSQPPLPDPELFIRWLQLATFMPAMQFSHLPSEYRSDLVTR 808
            :||.::||:.:.||.....|          |:.||:||||::|.||||||||..|..|.:::|.
Human   549 ILPDMVGGNAVPQRTAGGDV----------PERELYIRWLEVAAFMPAMQFSIPPWRYDAEVVA- 602

  Fly   809 VAQELKEVRQLIVIPLLKKYLNPSMNEGLPLVRPLWMMDPHDPACLIVSDEFSVGEELIVAPILH 873
            :||:...:|..:|.|||.:......:.|.|:|||||.:.|.|.....:..:|.:|:.|:|||:|.
Human   603 IAQKFAALRASLVAPLLLELAGEVTDTGDPIVRPLWWIAPGDETAHRIDSQFLIGDTLLVAPVLE 667

  Fly   874 ANREEREVYLPQGVWKDGIDGSLRKGSRWMHGYRVPKDKIAYF 916
            ..::||:||||.|.|:........|....:..|.|..|:||||
Human   668 PGKQERDVYLPAGKWRSYKGELFDKTPVLLTDYPVDLDEIAYF 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33080	NP_788858.1	GH31_NET37	511..888	CDD:269878	121/388 (31%)
MYORG	NP_065753.2	GH31_NET37	314..682	CDD:269878	121/388 (31%)