DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3149 and AT5G07630

DIOPT Version :9

Sequence 1:	NP_572246.1	Gene:	CG3149 / 31489	FlyBaseID:	FBgn0027564	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_196380.5	Gene:	AT5G07630 / 830656	AraportID:	AT5G07630	Length:	611	Species:	Arabidopsis thaliana

Alignment Length:	561	Identity:	163/561 - (29%)
Similarity:	267/561 - (47%)	Gaps:	85/561 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 FSIIFQILCRILTFGINAYIVRHVGREVLGIMNVRLLLLESTLLFLSREAINRAALSANAQQG-- 77
            ||:..|.:.|.:.|..|::||||:......:..::..|..:.:||||||...||.|.|..::.
plant   106 FSLSRQFISRSIPFVFNSWIVRHLTERDYALYAIQFHLFVTCVLFLSREGFRRACLRAGTKRDGP 170

  Fly    78 -DRCSWAQLINQMWLTVPI-CAVLCAPCLYI-WLNWLSAVDAIYASQYEFACYAVAFSCVLELMA 139
             ...:..:::...|:|||: .|:..|.|::: |...||     |:..|..|.:...|:|||||||
plant   171 ESEENVTRILKVAWVTVPLGIAITIAACIFVLWWQNLS-----YSDPYAQAIWIHGFACVLELMA 230

  Fly   140 ESAVFVAQVFCFVKLKILLNTLHILVRS-AIFLWIVTGDRSAAINAFAIAQLSSAVTIVLGQYGF 203
            |....::|....::|::::.|:..|.|. .::..:|.......:..||::|::...::.:|.:.
plant   231 EPLYILSQTLLKLQLRLIVETVATLARCVTLYSLLVMQTNMEKVIIFALSQVAYGGSLFIGYWA- 294

  Fly   204 FYFYLKGFKDFVTQQAKKKPVAPKAWQVSLYEHMDDFPFKQLSDFLPGVMFNPNGKHFNRELQTL 268
             ||.:.|                      :|...:.|||:      ||     |...|:.:|..:
plant   295 -YFLICG----------------------VYRSSNLFPFR------PG-----NFMDFDNDLSKM 325

  Fly   269 TLSFVKQGVLKQILTEGEKYVM--SVSPVLSFGEQATYDVVNNLGSMAARFIFRPIEDSSYFYFT 331
            ...|..|...|.||.||||.|:  ..:|.    .||.|.:|:.|||:..|.:|.|.|:|||..|.
plant   326 CKLFTFQSFRKLILQEGEKLVLVWLDTPY----NQAVYGIVDKLGSLVVRMVFLPFEESSYTIFA 386

  Fly   332 QTLSRDIKLAKQPQERVRQASSVLNNLLLGVSSIGLIAFTFGQSYSYPVL-LLYGGPDFVAGGLP 395
            :..|.|.      |||.::....|...|..|..||||...||.||||.:: ||||  :..:.|..
plant   387 RFASGDY------QERNKKLGIYLTVALKLVILIGLIFMAFGPSYSYSLIRLLYG--EKWSDGEA 443

  Fly   396 QSLLQWHCLAIYLLAVNGISEGYMFATNTSRDIDKYNYLMAIFSVSFLVLSYILTGIFGPVGFIF 460
            ...||::||.|.:||:||.||.::.|..|..::::.|.::.|||:.::.|:.:|....|.:|.|.
plant   444 SLALQFYCLYIIVLAMNGTSEAFLHAVGTKNELERSNDMLLIFSLIYVALNILLIRSAGAIGLIM 508

  Fly   461 ANCINMLSRILYSTYYIRHQYRPLSLDPLLGLWPGKLFGCTLFLAGIVC------------YWYQ 513
            ||.:||:.||:||..:|:..::..|.......:|  |....|.|:.|:.            :|
plant   509 ANSLNMIFRIIYSGRFIQRYFQGTSSFSFRKCFP--LGWQILILSSIITLISEKTILDRKNFW-- 569

  Fly   514 SSDLATHLGVGVLAGLACLLSWALAHRDLVRLAWRYGRRIK 554
             .....|.|:||:.  .||.:..:..|:.|     :.:|||
plant   570 -ETFPLHFGIGVIC--FCLSAIVIYRRERV-----FIKRIK 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3149	NP_572246.1	Rft-1	8..547	CDD:282375	160/552 (29%)
AT5G07630	NP_196380.5	MATE_rft1	99..531	CDD:240535	145/476 (30%)
AT5G07630	NP_196380.5	RfbX	100..605	CDD:225153	163/561 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	195	1.000	Domainoid score	I914
eggNOG	1	0.900	-	-		E1_KOG2864
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5343
Inparanoid	1	1.050	195	1.000	Inparanoid score	I1350
OMA	1	1.010	-	-		QHG54409
OrthoDB	1	1.010	-	-		D582756at2759
OrthoFinder	1	1.000	-	-		FOG0004239
OrthoInspector	1	1.000	-	-		oto3631
orthoMCL	1	0.900	-	-		OOG6_103267
Panther	1	1.100	-	-	LDO	PTHR13117
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4039
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840