Protein Alignment Sirt4 and HST1

DIOPT Version :9

• Sequence 1: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_014573.1
• Gene: HST1 / 854086
• SGDID: S000005429
• Length: 503
• Species: Saccharomyces cerevisiae
• Alignment Length: 311
• Identity: 71/311 - (22%)
• Similarity: 119/311 - (38%)
• Gaps: 85/311 - (27%)

  Fly    37 RLEDF---------LLSKPNVLVLTGAGISTESGIPDYRSEGVGLYARSNHKPVQHME------- 85
            ||.:|         |.:...:|||||||:||..||||:|| ..|.|::..|..::..:
Yeast   183 RLPNFNTIDHFTATLRNAKKILVLTGAGVSTSLGIPDFRS-SEGFYSKIRHLGLEDPQDVFNLDI 246

  Fly    86 FVKSSAVRKRYWARNFVGWPKFSATQPNATHHALARFEREERVQAVVTQNVDRLHTKAG--SRNV 148
            |::..:|   ::....:..|..:...|  .|..:...:.:.::....|||:|.|.:.||  ...:
Yeast   247 FLQDPSV---FYNIAHMVLPPENMYSP--LHSFIKMLQDKGKLLRNYTQNIDNLESYAGIDPDKL 306

  Fly   149 VEVHGSGYVVKCLSCEYRIDRHEFQSILASLNPAFKDAPDMIRPDGDVEIPLEYIENFRIPECTQ 213
            |:.|||.....|::|.::|...:.                           .|.|.|..:|.|..
Yeast   307 VQCHGSFATASCVTCHWQIPGEKI---------------------------FENIRNLELPLCPY 344

  Fly   214 C------------------------------GGDLKPEIVFFGDSVPRPRVDQIAGMVYNSDGLL 248
            |                              .|.|||::.|||:::|......|...:...|.|:
Yeast   345 CYQKRKQYFPMSNGNNTVQTNINFNSPILKSYGVLKPDMTFFGEALPSRFHKTIRKDILECDLLI 409

  Fly   249 VLGSSLLVFSGYRVVLQTKDLKLPVGIVNIG-ETRADHLADIKISAKCGDV 298
            .:|:||.|.....:|..... .:|..::|.. .|.|:.  |:.:...|.||
Yeast   410 CIGTSLKVAPVSEIVNMVPS-HVPQILINRDMVTHAEF--DLNLLGFCDDV 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	70/310 (23%)
HST1	NP_014573.1	DUF592	53..207	CDD:368003	6/23 (26%)
		SIRT1	201..461	CDD:238699	67/293 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810