Protein Alignment Sirt4 and Sirt3

DIOPT Version :10

• Sequence 1: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: XP_063142583.1
• Gene: Sirt3 / 293615
• RGDID: 1308374
• Length: 347
• Species: Rattus norvegicus
• Alignment Length: 264
• Identity: 75/264 - (28%)
• Similarity: 116/264 - (43%)
• Gaps: 54/264 - (20%)

  Fly    48 VLVLTGAGISTESGIPDYRSEGVGLYARSNHKPVQHMEFVKSSAVRKRYWARNFVGWPKFSAT-- 110
            |:|:.||||||.|||||:||.|.|||:......:.:.|.:    ....::..|    ||...|
  Rat    88 VVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAI----FELGFFFHN----PKPFFTLA 144

  Fly   111 --------QPNATHHALARFEREERVQAVVTQNVDRLHTKAG--SRNVVEVHGSGYVVKCLSCEY 165
                    :||..|:.|.....:|.:..:.|||:|.|...:|  :..:||.|||.....|..|
  Rat   145 KELYPGHYRPNVAHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGSFVSATCTVC-- 207

  Fly   166 RIDRHEFQSILASLNPAFKDAPDMIRPDGDVEIPLEYIENFRIPECTQCGGDLKPEIVFFGDSVP 230
               |..|..             :.||.|         :...|:|.|..|.|.:||:|||||:.:|
  Rat   208 ---RRSFPG-------------EDIRAD---------VMADRVPRCPVCTGVVKPDIVFFGEQLP 247

  Fly   231 RPRVDQIAGMVYNSDGLLVLGSSLLVFSGYRVVLQTKDLKLPVGIVNIGETRADHLADIKISAKC 295
            ...:..:|.... :|.||:||:||.| ..:..:.::....:|..::|     .|.:....:|.:.
  Rat   248 ARFLLHVADFAL-ADLLLILGTSLEV-EPFASLSESVQKSVPRLLIN-----RDLVGSFALSPRR 305

  Fly   296 GDVI 299
            .||:
  Rat   306 KDVV 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	74/262 (28%)
Sirt3	XP_063142583.1	None