Protein Alignment Sirt4 and Sirt3

DIOPT Version :9

• Sequence 1: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: XP_006230588.1
• Gene: Sirt3 / 293615
• RGDID: 1308374
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 264
• Identity: 75/264 - (28%)
• Similarity: 116/264 - (43%)
• Gaps: 54/264 - (20%)

  Fly    48 VLVLTGAGISTESGIPDYRSEGVGLYARSNHKPVQHMEFVKSSAVRKRYWARNFVGWPKFSAT-- 110
            |:|:.||||||.|||||:||.|.|||:......:.:.|.:    ....::..|    ||...|
  Rat    75 VVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAI----FELGFFFHN----PKPFFTLA 131

  Fly   111 --------QPNATHHALARFEREERVQAVVTQNVDRLHTKAG--SRNVVEVHGSGYVVKCLSCEY 165
                    :||..|:.|.....:|.:..:.|||:|.|...:|  :..:||.|||.....|..|
  Rat   132 KELYPGHYRPNVAHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGSFVSATCTVC-- 194

  Fly   166 RIDRHEFQSILASLNPAFKDAPDMIRPDGDVEIPLEYIENFRIPECTQCGGDLKPEIVFFGDSVP 230
               |..|..             :.||.|         :...|:|.|..|.|.:||:|||||:.:|
  Rat   195 ---RRSFPG-------------EDIRAD---------VMADRVPRCPVCTGVVKPDIVFFGEQLP 234

  Fly   231 RPRVDQIAGMVYNSDGLLVLGSSLLVFSGYRVVLQTKDLKLPVGIVNIGETRADHLADIKISAKC 295
            ...:..:|.... :|.||:||:||.| ..:..:.::....:|..::|     .|.:....:|.:.
  Rat   235 ARFLLHVADFAL-ADLLLILGTSLEV-EPFASLSESVQKSVPRLLIN-----RDLVGSFALSPRR 292

  Fly   296 GDVI 299
            .||:
  Rat   293 KDVV 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	74/262 (28%)
Sirt3	XP_006230588.1	SIRT1	74..308	CDD:238699	75/264 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810