Protein Alignment Sirt4 and sir-2.4

DIOPT Version :9

• Sequence 1: NP_572241.2
• Gene: Sirt4 / 31480
• FlyBaseID: FBgn0029783
• Length: 312
• Species: Drosophila melanogaster
• Sequence 2: NP_491733.2
• Gene: sir-2.4 / 182284
• WormBaseID: WBGene00004803
• Length: 292
• Species: Caenorhabditis elegans
• Alignment Length: 307
• Identity: 72/307 - (23%)
• Similarity: 120/307 - (39%)
• Gaps: 74/307 - (24%)

  Fly    28 KPVVEDD----IKRL----EDFLLSKPN---VLVLTGAGISTESGIPDYR-SEGV-GLYARSNHK 79
            ||.:.|.    |::|    ..|:.:|..   :.||.|||:||.|.:||:| .:|| .|.|..
 Worm    20 KPEIRDTETEIIEKLRTLYNHFVQAKQTGKPIFVLIGAGVSTGSKLPDFRGKQGVWTLQAEG--- 81

  Fly    80 PVQHMEFVKSSAVRKRYWARNFVGWPKFSATQPNATHHALARFEREERVQAVVTQNVDRLHTKAG 144
              :|.|.|                  .|...:|..:|.::....:...::.::|||||.|..|.|
 Worm    82 --KHAEGV------------------DFQVARPGVSHKSILALHKAGYIKTIITQNVDGLDRKVG 126

  Fly   145 --SRNVVEVHGSGYVVKCLSCEYRIDRHEFQSILASLNPAFKDAPDMIRPDGDVEIPLEYIENFR 207
              ..:::||||:.::..|.||.....|.|   |:.|:.         :.|.|
 Worm   127 IPVEDLIEVHGNLFLEVCQSCFSEYVREE---IVMSVG---------LCPTG------------- 166

  Fly   208 IPEC-------TQCGGDLKPEIVFFGDSVPRPRVDQIAGMVYNSDGLLVLGSSLLVFSGYRVVLQ 265
             ..|       ..|.|.|:...:.:...:....:|:|......:..||.:|:||.:.....:.|.
 Worm   167 -RNCEGNKRTGRSCRGKLRDATLDWDTEISLNHLDRIRKAWKQTSHLLCIGTSLEIIPMGSLPLD 230

  Fly   266 TKDLKLPVGIVNIGETRADHLADIKISAKCGDVIPKLFDFRNSKSVS 312
            .|...:....:|..||..:.:.:..|.|   ||...|:...|:..|:
 Worm   231 AKSKGIKTTTINYQETAHEKIVETAIHA---DVKLILYSLCNALGVN 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt4	NP_572241.2	SIRT4	38..299	CDD:238700	64/278 (23%)
sir-2.4	NP_491733.2	SIR2	49..259	CDD:294129	60/261 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810