Protein Alignment SK and Kcnn4

DIOPT Version :10

• Sequence 1: NP_001284887.1
• Gene: SK / 31456
• FlyBaseID: FBgn0029761
• Length: 1174
• Species: Drosophila melanogaster
• Sequence 2: XP_006228531.1
• Gene: Kcnn4 / 65206
• RGDID: 621476
• Length: 429
• Species: Rattus norvegicus
• Alignment Length: 380
• Identity: 159/380 - (41%)
• Similarity: 226/380 - (59%)
• Gaps: 32/380 - (8%)

  Fly   515 YSTALKTLISVSTVILLGLIVAYHALEVQVRLFMIDNCADDWRIAMTWQRISQIGLELFICAIHP 579
            |...:|.||::||..||.|||.:||.|||  |||.||...|||:|:|.::::||.|||.:|.:||
  Rat    62 YLLLVKCLITLSTAFLLCLIVVFHAKEVQ--LFMTDNGLRDWRVALTRRQVAQILLELLVCGVHP 124

  Fly   580 IPGEYYFQWTTKLANKNKTIGTEMVPY----------DVALSLPMFLRLYLICRVMLLHSKLFTD 634
            :|          |.:.:.|:..|....          :..|||.|.|||||:.|.:||.|.:..:
  Rat   125 VP----------LRSPHCTLAGEATDSQAWPGFLGEGEALLSLAMLLRLYLVPRAVLLRSGVLLN 179

  Fly   635 ASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNAM 699
            ||.|||||||::.|...||.|..|...||.:||...:.||:..:|.|...||.......:|.:.:
  Rat   180 ASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLTDTL 244

  Fly   700 WLIAITFLSVGFGDIVPNTYCGRGIAVSTGIMGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQ 764
            |||.||||::|:||:||.|..|:.:.:.||:||..|||||||||:||||..:|||||||||||..
  Rat   245 WLIPITFLTIGYGDVVPGTLWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIH 309

  Fly   765 LTKRLKNAAANVLRETWLIYKHTRLVKRVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMDNANTI 829
            ..|.:|.:||.:|:|.|:.|||||   |.:....|.||||.|.||:..|:|::..|||.:..|::
  Rat   310 YAKEMKESAARLLQEAWMYYKHTR---RKDSRAARRHQRKMLAAIHTFRQVRLKHRKLREQVNSM 371

  Fly   830 TDMAKTQNTVYEIISDMSSRQDAIEERLTNLEDKMQSIQEHMESLPDLLSRCLTQ 884
            .|::|....:.::...:|:...|:|:|:..|..|       :::|.:|||..|.|
  Rat   372 VDISKMHMILCDLQLGLSASHLALEKRIDGLAGK-------LDALTELLSTALQQ 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SK	NP_001284887.1	SK_channel	469..581	CDD:460958	34/65 (52%)
		Ion_trans_2	669..748	CDD:462301	36/78 (46%)
		CaMBD	762..836	CDD:460739	30/73 (41%)
Kcnn4	XP_006228531.1	SK_channel	<59..126	CDD:460958	34/65 (52%)
		Ion_trans_2	<240..293	CDD:462301	30/52 (58%)
		CaMBD	307..378	CDD:460739	30/73 (41%)