DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snf and snrpb2

DIOPT Version :9

Sequence 1:	NP_511045.1	Gene:	snf / 31442	FlyBaseID:	FBgn0003449	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_001011120.1	Gene:	snrpb2 / 496533	XenbaseID:	XB-GENE-1010457	Length:	223	Species:	Xenopus tropicalis

Alignment Length:	223	Identity:	146/223 - (65%)
Similarity:	176/223 - (78%)	Gaps:	7/223 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEMLPNQTIYINNLNEKIKKEELKKSLYAIFSQFGQILDIVALKTLKMRGQAFVIFKEIGSASNA 65
            |::.||.|:|||||.:|:||.|||:||||:|||||.::|||||||:||||||||||||:.||:||
Frog     1 MDIRPNHTVYINNLCDKVKKPELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELSSATNA 65

  Fly    66 LRTMQGFPFYDKPMQIAYSKSDSDIVAKIKGTFKERPKKVKPPKPAPGTDEKKDKKKKPSSAENS 130
            ||.:||||||:|||:|.|:|||||::.|:||||.::.||.:..|............|||:.|.|:
Frog    66 LRQLQGFPFYNKPMRIQYAKSDSDVILKMKGTFADKEKKKEKKKAKAQEQAANAANKKPALASNA 130

  Fly   131 N--PNAQTEQ-----PPNQILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPNRHDIAFVEFTTE 188
            |  |.|...|     |||.||||.||||||||||||||||||||||||||||.|||||||||..|
Frog   131 NNAPGASQNQQVPDNPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENE 195

  Fly   189 LQSNAAKEALQGFKITPTHAMKITFAKK 216
            .::.||::|||||||||:||||||:|.|
Frog   196 TEAGAARDALQGFKITPSHAMKITYANK 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snf	NP_511045.1	RRM	<5..177	CDD:223796	116/178 (65%)
		RRM_SF	6..96	CDD:302621	64/89 (72%)
		RRM2_SNF	137..216	CDD:240923	64/83 (77%)
snrpb2	NP_001011120.1	RRM1_U2B	6..96	CDD:240922	64/89 (72%)
snrpb2	NP_001011120.1	RRM_SF	144..223	CDD:388407	63/78 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6359
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	293	1.000	Inparanoid score	I2722
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1608132at2759
OrthoFinder	1	1.000	-	-		FOG0001375
OrthoInspector	1	1.000	-	-		otm49059
Panther	1	1.100	-	-	O	PTHR10501
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1270
SonicParanoid	1	1.000	-	-		X1105
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.190