Protein Alignment Cdk7 and CDK1

DIOPT Version :10

• Sequence 1: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001777.1
• Gene: CDK1 / 983
• HGNCID: 1722
• Length: 297
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 125/296 - (42%)
• Similarity: 181/296 - (61%)
• Gaps: 20/296 - (6%)

  Fly    10 ERYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENI 74
            |.|.|:..:|||.:..|||.|...|.|:||:|||:..|.|   :|:..||:|||.:|:||:|.||
Human     2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEE---EGVPSTAIREISLLKELRHPNI 63

  Fly    75 IGLVDVFGQLSNVSLVFDFMDTDLEVII--------KDNKIILTQANIKAYAIMTLKGLEYLHLN 131
            :.|.||..|.|.:.|:|:|:..||:..:        .|:.:      :|:|....|:|:.:.|..
Human    64 VSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSL------VKSYLYQILQGIVFCHSR 122

  Fly   132 WILHRDLKPNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLFGARQYGTGVDM 196
            .:|||||||.|||::..|.:|:.|||||::||.|.|:|||.|||.||||||:|.|:.:|.|.||:
Human   123 RVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDI 187

  Fly   197 WAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKLHDYLQ-FRNF-PGTPLDN 259
            |::|.|.|||..:.|...|||::|||.|||..||||....||.:..|.||.. |..: ||:...:
Human   188 WSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASH 252

  Fly   260 IFTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYF 295
            :.....|.| .|:.::...:|.:|:|.:.||:.|||
Human   253 VKNLDENGL-DLLSKMLIYDPAKRISGKMALNHPYF 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk7	NP_511044.1	STKc_CDK7	11..308	CDD:270833	124/295 (42%)
CDK1	NP_001777.1	STKc_CDK1_euk	3..287	CDD:270845	122/293 (42%)