Protein Alignment Cdk7 and SSN3

DIOPT Version :10

• Sequence 1: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_015283.1
• Gene: SSN3 / 856065
• SGDID: S000005963
• Length: 555
• Species: Saccharomyces cerevisiae
• Alignment Length: 304
• Identity: 111/304 - (36%)
• Similarity: 161/304 - (52%)
• Gaps: 25/304 - (8%)

  Fly    22 QFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENIIGLVDVFGQLSN 86
            |..|:.|...||...|...|..|.|..:....||:::|.||:.:.:||.::::..||::|.:...
Yeast   167 QKQTLIKKPLTVFYAIKKFKTEKDGVEQLHYTGISQSACREMALCRELHNKHLTTLVEIFLERKC 231

  Fly    87 VSLVFDFMDTDLEVII----KDNKIILTQANIKAYAIMTLKGLEYLHLNWILHRDLKPNNLLVNS 147
            |.:|:::.:.||..||    ...|.::....:::.....|.|:.|||.||:|||||||.|::|..
Yeast   232 VHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTI 296

  Fly   148 DGILKIGDFGLAKSFGSP-NRIYTHH--VVTRWYRSPELLFGARQYGTGVDMWAVGCILAELMLR 209
            ||.:||||.|||:.|.:. ..:||..  |||.|||:||||.|||.|...||:|:||||.|||:..
Yeast   297 DGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGL 361

  Fly   210 VPFMPGDS-----------DLDQLTRIFSTLGTPTEAEWPHLSKLHDYLQFRNFPGTPLDNIFT- 262
            .|...|:.           .::||.||...||||.:..||:|.|..:|.|...|| ...||:.|
Yeast   362 QPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITKFP-KYRDNLATW 425

  Fly   263 ---AAGND--LIHLMQRLFAMNPLRRVSCREALSMPYFANKPAP 301
               |.|.|  .:.|:..|...:|::|:....||...||.....|
Yeast   426 YHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTESDIP 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk7	NP_511044.1	STKc_CDK7	11..308	CDD:270833	111/304 (37%)
SSN3	NP_015283.1	STKc_CDK8_like	74..463	CDD:270834	108/296 (36%)