Protein Alignment Cdk7 and FUS3

DIOPT Version :10

• Sequence 1: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_009537.1
• Gene: FUS3 / 852265
• SGDID: S000000112
• Length: 353
• Species: Saccharomyces cerevisiae
• Alignment Length: 319
• Identity: 115/319 - (36%)
• Similarity: 171/319 - (53%)
• Gaps: 34/319 - (10%)

  Fly    16 SFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENIIGLV-- 78
            |.||||.:..|..|....|.:|||:|||:.   .|......|| |||||||:..:|||||.:.
Yeast    17 SLLGEGAYGVVCSATHKPTGEIVAIKKIEP---FDKPLFALRT-LREIKILKHFKHENIITIFNI 77

  Fly    79 ---DVFGQLSNVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLEYLHLNWILHRDLKP 140
               |.|...:.|.::.:.|.|||..:|...  :|:..:|:.:...||:.::.||.:.::||||||
Yeast    78 QRPDSFENFNEVYIIQELMQTDLHRVISTQ--MLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKP 140

  Fly   141 NNLLVNSDGILKIGDFGLAKSF-----------GSPNRIYTHHVVTRWYRSPELLFGARQYGTGV 194
            :|||:||:..||:.|||||:..           |..:.: |.:|.|||||:||::..:.:|...:
Yeast   141 SNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGM-TEYVATRWYRAPEVMLTSAKYSRAM 204

  Fly   195 DMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTE------AEWPHLSKLHDYLQ-FRNF 252
            |:|:.|||||||.||.|..||.....||..||..:|||..      .|.|   :..:|:: ...:
Yeast   205 DVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESP---RAREYIKSLPMY 266

  Fly   253 PGTPLDNIFTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYFANKPAPTVGPK-LPMP 310
            |..||:.:|.......|.|:||:...:|.:|::.:|||..||......|...|: .|:|
Yeast   267 PAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDEPEGEPIP 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk7	NP_511044.1	STKc_CDK7	11..308	CDD:270833	113/315 (36%)
FUS3	NP_009537.1	STKc_ERK1_2_like	7..353	CDD:270839	115/319 (36%)