Protein Alignment Cdk7 and Cdk10

DIOPT Version :10

• Sequence 1: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: XP_038953809.1
• Gene: Cdk10 / 361434
• RGDID: 1304851
• Length: 405
• Species: Rattus norvegicus
• Alignment Length: 357
• Identity: 128/357 - (35%)
• Similarity: 189/357 - (52%)
• Gaps: 52/357 - (14%)

  Fly    10 ERYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENI 74
            :.:.||:.:|||.:..||:||||.|::|||:||::   .:..:|||..::||||.:|..|:|.||
  Rat    47 KEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVR---MDKEKDGIPISSLREITLLLRLRHPNI 108

  Fly    75 IGLVDVF--GQLSNVSLVFDFMDTDLEVIIKDNKIILTQA------------------------- 112
            :.|.:|.  ..|.::.||..:.:.||..::::.....::|
  Rat   109 VELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQFCLSCAGHSHSHTLEVLVTSRQRV 173

  Fly   113 ----------NIKAYAIMTLKGLEYLHLNWILHRDLKPNNLLVNSDGILKIGDFGLAKSFGSPNR 167
                      .:|...:..|:||:|||.::|:|||||.:|||:...|.:|..|||||:::|.|.:
  Rat   174 DALHPVSGPPQVKCILLQVLRGLQYLHRSFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVK 238

  Fly   168 IYTHHVVTRWYRSPELLFGARQYGTGVDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTP 232
            ..|..|||.|||:||||.|.....|.:||||||||||||:...|.:||.|::.|:..|...||||
  Rat   239 PMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQIDLIVQLLGTP 303

  Fly   233 TEAEWPHLSKLHDYLQF--RNFPGTPLDNIFTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYF 295
            :|..||..|||....|:  |..|...|.:.|.......:.|:..||..:|.:|.:..:.|...||
  Rat   304 SENIWPGFSKLPLAGQYSLRKQPYNNLKHKFPWLSEAGLRLLNFLFMYDPKKRATAGDCLESSYF 368

  Fly   296 ANKPAPTVGPKLPMPS--------AILAAKEG 319
            ..||.| ..|:| ||:        |..||.||
  Rat   369 KEKPLP-CEPEL-MPTFPHHRNKRAAPAATEG 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk7	NP_511044.1	STKc_CDK7	11..308	CDD:270833	120/335 (36%)
Cdk10	XP_038953809.1	STKc_CDK10	41..384	CDD:173742	123/341 (36%)