Protein Alignment Cdk7 and pef1

DIOPT Version :10

• Sequence 1: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_587921.1
• Gene: pef1 / 2539366
• PomBaseID: SPCC16C4.11
• Length: 288
• Species: Schizosaccharomyces pombe
• Alignment Length: 292
• Identity: 123/292 - (42%)
• Similarity: 177/292 - (60%)
• Gaps: 17/292 - (5%)

  Fly    12 YAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENIIG 76
            |.:|..||||.:|.|||.::.||.:|||:|.|    |.||.:|...||:|||.:::||:|.||:.
pombe     3 YQRLEKLGEGTYAHVYKGQNRVTGEIVALKVI----RIDADEGTPSTAIREISLMKELRHPNIMS 63

  Fly    77 LVDVFGQLSNVSLVFDFMDTDLEVIIK--DNKIILTQANIKAYAIMTLKGLEYLHLNWILHRDLK 139
            |.||....:.:.|||::|:.||:..:.  .|:..|..:.:|.:....|||:.:.|.|.:||||||
pombe    64 LSDVLQTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHENRVLHRDLK 128

  Fly   140 PNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLFGARQYGTGVDMWAVGCILA 204
            |.|||:||.|.||:.|||||:|.|.|...:::.|||.|||:|::|.|:|.|.|.:|:|:||||:|
pombe   129 PQNLLINSRGELKLADFGLARSIGIPVNTFSNEVVTLWYRAPDVLLGSRVYSTSIDIWSVGCIMA 193

  Fly   205 ELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKLHDYLQFRNFPGTPLDNI------FTA 263
            |:....|...|.::.|||.:||..||||||..||.:|.|.:|..  .||.....::      |..
pombe   194 EMATGRPLFAGSNNEDQLLKIFRLLGTPTEQSWPGISLLPEYKP--TFPIYKAQDLAYLFPTFDP 256

  Fly   264 AGNDLIHLMQRLFAMNPLRRVSCREALSMPYF 295
            .|.||:..|.||   .|..|.:.::||...:|
pombe   257 LGLDLLRRMLRL---QPELRTTGQDALQHAWF 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk7	NP_511044.1	STKc_CDK7	11..308	CDD:270833	123/292 (42%)
pef1	NP_587921.1	Protein Kinases, catalytic domain	2..285	CDD:473864	122/290 (42%)