Protein Alignment Cdk7 and MAPK15

DIOPT Version :10

• Sequence 1: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: XP_011515227.1
• Gene: MAPK15 / 225689
• HGNCID: 24667
• Length: 565
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 109/312 - (34%)
• Similarity: 167/312 - (53%)
• Gaps: 37/312 - (11%)

  Fly    23 FATVYKARDTVTNQIVAVKKIKKGSRE--DARD---------------GINRTALREIKILQEL- 69
            :..|:||.|..|.::||:|||....|:  ||:|               .:.|| .|||.:|||.
Human    26 YGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQDMGFLLAPPTHTPVFLSLQRT-FREITLLQEFG 89

  Fly    70 QHENIIGLVDVFGQLS--NVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLEYLHLNW 132
            .|.|||.|:||....:  ::.|||:||||||..:|:... :|...::::.....|:...:||...
Human    90 DHPNIISLLDVIRAENDRDIYLVFEFMDTDLNAVIRKGG-LLQDVHVRSIFYQLLRATRFLHSGH 153

  Fly   133 ILHRDLKPNNLLVNSDGILKIGDFGLAKSFGS-----PNRIYTHHVVTRWYRSPELLFGARQYGT 192
            ::|||.||:|:|::::..:|:.|||||:|.|.     .::..|.:|.|||||:||:|..:.:|..
Human   154 VVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHRYTL 218

  Fly   193 GVDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHL------SKLHDYLQFRN 251
            |||||::||||.|::...|..||.|.|.||..|..|:..|:|.:...|      |.||   |..:
Human   219 GVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSGCRASVLH---QLGS 280

  Fly   252 FPGTPLDNIFTA-AGNDLIHLMQRLFAMNPLRRVSCREALSMPYFANKPAPT 302
            .|...||.:... ...:.:.|::||....|.:|:|..:||..||......|:
Human   281 RPRQTLDALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQHPYVQRFHCPS 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk7	NP_511044.1	STKc_CDK7	11..308	CDD:270833	109/312 (35%)
MAPK15	XP_011515227.1	STKc_MAPK15-like	25..364	CDD:270841	109/312 (35%)