Protein Alignment Cdk7 and Cdk5

DIOPT Version :10

• Sequence 1: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: XP_315787.4
• Gene: Cdk5 / 1276441
• VectorBaseID: AGAMI1_003707
• Length: 289
• Species: Anopheles gambiae
• Alignment Length: 294
• Identity: 123/294 - (41%)
• Similarity: 179/294 - (60%)
• Gaps: 17/294 - (5%)

  Fly    10 ERYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENI 74
            ::|.||..:|||.:.||:|.::..|.:|||:|:::   .::..:|:..:|||||.:|:||:|:||
Mosquito     2 QKYEKLEKIGEGTYGTVFKGKNRDTLEIVALKRVR---LDEDDEGVPSSALREICLLKELKHKNI 63

  Fly    75 IGLVDVFGQLSNVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLEYLHLNWILHRDLK 139
            :.|.||......::|||:..|.||:.........:....:|::....|:||.:.|.:.:||||||
Mosquito    64 VRLYDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDPDVVKSFMYQLLRGLAFCHSHNVLHRDLK 128

  Fly   140 PNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLFGARQYGTGVDMWAVGCILA 204
            |.|||:|.:|.||:.|||||::||.|.:.|:..|||.|||.|::||||:.|.|.:|||:.|||.|
Mosquito   129 PQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCIFA 193

  Fly   205 ELM-LRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKLHDYLQFRNFPGT-------PLDNIF 261
            ||. ...|..||....|||.|||..||||.|..||.:::|.||..|..:|.|       |..|
Mosquito   194 ELANAGRPLFPGSDVDDQLKRIFKLLGTPEEENWPGITQLSDYKPFPLYPPTTSWSQVVPRLN-- 256

  Fly   262 TAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYF 295
             :.|.|   |:|:|....||.|:|..:|:|.|||
Mosquito   257 -SKGRD---LLQKLLVCRPLLRLSAEQAMSHPYF 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk7	NP_511044.1	STKc_CDK7	11..308	CDD:270833	123/293 (42%)
Cdk5	XP_315787.4	STKc_CDK5	3..286	CDD:143344	121/291 (42%)