Protein Alignment Cdk7 and cdk12

DIOPT Version :10

• Sequence 1: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: XP_003200579.2
• Gene: cdk12 / 100149834
• ZFINID: ZDB-GENE-081104-294
• Length: 1293
• Species: Danio rerio
• Alignment Length: 362
• Identity: 106/362 - (29%)
• Similarity: 184/362 - (50%)
• Gaps: 55/362 - (15%)

  Fly    10 ERYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENI 74
            :::..:..:|||.:..||||:|..|.::||:||::   .::.::|...||:||||||::|.|.::
Zfish   673 DKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVR---LDNEKEGFPITAIREIKILRQLNHRSV 734

  Fly    75 IGLVDVFGQLSNV----------SLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLEYLH 129
            :.:.::.....:.          .|||::||.||..:::...:..:..:::::....::||:|.|
Zfish   735 VNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVSFSHEHVQSFMRQLMEGLDYCH 799

  Fly   130 LNWILHRDLKPNNLLVNSDGILKIGDFGLAKSFGS-PNRIYTHHVVTRWYRSPELLFGARQYGTG 193
            ....||||:|.:|:|:|:.|.:|:.|||||:.:.| .:|.||:.|:|.|||.||||.|..:|...
Zfish   800 KKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYSPA 864

  Fly   194 VDMWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKLHDY------LQFRNF 252
            :|:|:.||||.||..:.|....:.:|.||..|....|:|..|.||.:.:|..:      .|:|.
Zfish   865 IDVWSCGCILGELFTKKPIFQANQELLQLELISRLCGSPCPAAWPDVIRLPYFNTMRPKKQYRR- 928

  Fly   253 PGTPLDNIFTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYFA----NKPAPTVGPKLP----- 308
               .|...|:......:.|:..:..::|.||.:..:||:..:..    ||..|   |.||
Zfish   929 ---RLREEFSFLPTPALDLLDHMLTLDPSRRCTAEQALASQFLCDVEPNKMPP---PDLPHWQDC 987

  Fly   309 -------------------MPSAILAAKEGANPQTGD 326
                               :|.|.:..||.|....|:
Zfish   988 HELWSKKRRRQRQSGVSEDLPVAKVPRKEPAGASGGE 1024

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk7	NP_511044.1	STKc_CDK7	11..308	CDD:270833	98/317 (31%)
cdk12	XP_003200579.2	STKc_CDK12	667..968	CDD:270847	94/301 (31%)