DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ovo and CG2202

DIOPT Version :9

Sequence 1:	NP_001162673.1	Gene:	ovo / 31429	FlyBaseID:	FBgn0003028	Length:	1351	Species:	Drosophila melanogaster
Sequence 2:	NP_572657.2	Gene:	CG2202 / 32014	FlyBaseID:	FBgn0030240	Length:	889	Species:	Drosophila melanogaster

Alignment Length:	180	Identity:	55/180 - (30%)
Similarity:	80/180 - (44%)	Gaps:	40/180 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  1149 QQQQQQQHHQHHSNSSASSNASSHGSAEALC--MGSSGGANE------DSSSGNNKFVCRVCMKT 1205
            ::.|.::|.:.|:           |....||  .|.|...|:      ...:|...:.||.|:|.
  Fly   609 ERAQLREHEKTHT-----------GQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRFCVKA 662

  Fly  1206 FSLQRLLNRHMKCHSDIKRYLCTFCGKGFNDTFDLKRHTRTHTGVRPYKCNLCEKSFTQRCSLES 1270
            |.....|..|.:.|:..|..||..|||.|:..::|..|.|||||.|||||:.|.|||||...|::
  Fly   663 FPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKA 727

  Fly  1271 HCQKVHSVQHQYAYKERRAKMYVCEECGHTTCEPEVHYLHLKN--NHPFS 1318
            |.:: |:           .:.|.|..|       :.::|.|.|  ||..|
  Fly   728 HIRR-HT-----------GERYKCPHC-------DAYFLQLYNMRNHCMS 758

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ovo	NP_001162673.1	C2H2 Zn finger	1199..1219	CDD:275368	7/19 (37%)
		zf-H2C2_2	1212..1235	CDD:290200	9/22 (41%)
		C2H2 Zn finger	1227..1247	CDD:275368	8/19 (42%)
		zf-H2C2_2	1239..1264	CDD:290200	16/24 (67%)
		C2H2 Zn finger	1255..1276	CDD:275368	9/20 (45%)
CG2202	NP_572657.2	zf-AD	45..121	CDD:285071
		C2H2 Zn finger	150..171	CDD:275368
		C2H2 Zn finger	192..213	CDD:275370
		C2H2 Zn finger	221..239	CDD:275370
		COG5048	<443..730	CDD:227381	45/131 (34%)
		C2H2 Zn finger	476..496	CDD:275368
		zf-H2C2_2	488..513	CDD:290200
		C2H2 Zn finger	504..525	CDD:275368
		C2H2 Zn finger	532..548	CDD:275368
		C2H2 Zn finger	573..593	CDD:275368
		C2H2 Zn finger	600..620	CDD:275368	2/10 (20%)
		zf-H2C2_2	613..637	CDD:290200	7/34 (21%)
		C2H2 Zn finger	628..648	CDD:275368	4/19 (21%)
		zf-H2C2_2	640..663	CDD:290200	5/22 (23%)
		C2H2 Zn finger	656..676	CDD:275368	7/19 (37%)
		C2H2 Zn finger	684..704	CDD:275368	8/19 (42%)
		zf-C2H2	684..704	CDD:278523	8/19 (42%)
		zf-H2C2_2	696..721	CDD:290200	16/24 (67%)
		C2H2 Zn finger	712..732	CDD:275368	9/20 (45%)
		C2H2 Zn finger	739..755	CDD:275368	5/22 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910