DRSC/TRiP Functional Genomics Resources

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Protein Alignment ovo and ZNF384

DIOPT Version :9

Sequence 1:NP_001162673.1 Gene:ovo / 31429 FlyBaseID:FBgn0003028 Length:1351 Species:Drosophila melanogaster
Sequence 2:NP_001372672.1 Gene:ZNF384 / 171017 HGNCID:11955 Length:608 Species:Homo sapiens


Alignment Length:424 Identity:96/424 - (22%)
Similarity:154/424 - (36%) Gaps:106/424 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   985 HGHGHDNSNMS-LPSPTAAAAAAAAAAAAAAAAAAHLQRPMSSSSSSGG-----TNSSNSSGGSS 1043
            |.......|:: :|.|:.....|..:.:         ||.....|.|.|     |:.|.|...::
Human    79 HSQASVTQNITVVPVPSTGLMTAGVSCS---------QRWRREGSQSRGPGLVITSPSGSLVTTA 134

  Fly  1044 NSPLLDANAAAAAAAALLDTKPLIQSLGLPPDLQLEFVN-------GGHGIKNPLAVENAHGGHH 1101
            :|......:|....:||   .|..|:|.:.|||..:..:       ||.|....:|.:...|...
Human   135 SSAQTFPISAPMIVSAL---PPGSQALQVVPDLSKKVASTLTEEGGGGGGGGGSVAPKPPRGRKK 196

  Fly  1102 R--------------IRNIDCIDDLSKHG--HHSQHQQQQGSPQQQNMQQSVQQQSVQ------- 1143
            :              :.:.:..||..|.|  :.|:.....|:.|...:..||...:..       
Human   197 KRMLESGLPEMNDPYVLSPEDDDDHQKDGKTYRSEGNCGTGNGQSLGLMDSVPGSTTNLLCDPGC 261

  Fly  1144 QQQSL---QQQQQQQHHQHHSNSS-------ASSNASSHGSAEALCMGSSGGANEDSSSGNNK-- 1196
            :..||   .:.:.|.|.:.|:.:.       :.:.|:|...|:.:.:.|  ||...|.:...|  
Human   262 RMCSLTFYSKSEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHS--GAKPYSCNFCEKSF 324

  Fly  1197 -----------------------FVCRVCMKTFSLQRLLNRHMKCHSDIKRYLCTFCGKGFNDTF 1238
                                   ..|..|.|||:....|.:|::.||..|.|.|::|.|.|....
Human   325 RQLSHLQQHTRIHSKMHTETIKPHKCPHCSKTFANTSYLAQHLRIHSGAKPYNCSYCQKAFRQLS 389

  Fly  1239 DLKRHTRTHTGVRPYKCNL--CEKSFTQRCSLESH-----------CQKVHSVQ--------HQY 1282
            .|::|||.|||.|||||..  |||:|||..:|:||           |...|...        |..
Human   390 HLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEVHLS 454

  Fly  1283 AYKERRAKMYVCEECGHTTCEPEVHYLHLKNNHP 1316
            .:..:.||:|.|..|............|::.::|
Human   455 THTVKHAKVYTCTICSRAYTSETYLMKHMRKHNP 488

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ovoNP_001162673.1 C2H2 Zn finger 1199..1219 CDD:275368 7/19 (37%)
zf-H2C2_2 1212..1235 CDD:290200 9/22 (41%)
C2H2 Zn finger 1227..1247 CDD:275368 8/19 (42%)
zf-H2C2_2 1239..1264 CDD:290200 16/26 (62%)
C2H2 Zn finger 1255..1276 CDD:275368 11/33 (33%)
ZNF384NP_001372672.1 C2H2 Zn finger 261..281 CDD:275368 4/19 (21%)
COG5048 <284..486 CDD:227381 53/203 (26%)
C2H2 Zn finger 289..309 CDD:275368 3/19 (16%)
C2H2 Zn finger 317..337 CDD:275368 1/19 (5%)
C2H2 Zn finger 350..370 CDD:275368 7/19 (37%)
C2H2 Zn finger 378..398 CDD:275368 8/19 (42%)
C2H2 Zn finger 406..428 CDD:275368 10/21 (48%)
C2H2 Zn finger 436..456 CDD:275368 3/19 (16%)
C2H2 Zn finger 466..486 CDD:275368 3/19 (16%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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