Protein Alignment Ptp4E and ida-1

DIOPT Version :10

• Sequence 1: NP_525076.2
• Gene: Ptp4E / 31425
• FlyBaseID: FBgn0004368
• Length: 1767
• Species: Drosophila melanogaster
• Sequence 2: NP_498245.2
• Gene: ida-1 / 175807
• WormBaseID: WBGene00002048
• Length: 767
• Species: Caenorhabditis elegans
• Alignment Length: 725
• Identity: 167/725 - (23%)
• Similarity: 281/725 - (38%)
• Gaps: 185/725 - (25%)

  Fly   980 DFADVSVSTLMRSSAPISASYQT----LTAPPGKVDYFQPSDVQPGEVT-------FEWSLEPA- 1032
            ||..|      |..|.:.|..|.    ||..|..:|    .||.|..||       .|...||:
 Worm   110 DFCQV------RKPANVWALIQLIDTGLTEDPTILD----EDVNPENVTDEDMAQIIEQLKEPSL 164

  Fly  1033 -----------EQHGPID------YFRITCQNAD-DAADVSSYEFPVNATQGKIDGLVPGNHYIF 1079
                       .|:..:|      |.:....|.: |.:::|..:  :|...|:   ||.....:.
 Worm   165 PTEEDIEEALNAQNEDVDDEILDQYVQAVVNNENPDFSELSDGQ--LNILIGR---LVDLKKNVE 224

  Fly  1080 RIQAKSALGYGAEREHIQTMPILAPPVP------EPSVTPLEVSRTSSTIEISFRQGYFSNAHGM 1138
            ..:|:...|.| |:|       :|.|:.      |.::...::.:..   ||:  ||..:..|.:
 Worm   225 NEEAQLLTGDG-EQE-------MAVPLDDLEERGEQAILKKDIEQVG---EIN--QGLDNTEHKI 276

  Fly  1139 V--RSYTIIIAEDVG--------KNASGLEMPSWQDVQAYTVWLPYQAIEPYNPFLTSNGSRKSS 1193
            |  |...::...|..        ||...| ||..:.:| .|:.:|....  ::.|...||  :.|
 Worm   277 VKGRKDQVVTRVDANRVYLKVHLKNEDQL-MPLIEFLQ-NTIAIPNNLY--FDDFQFENG--QLS 335

  Fly  1194 LEAEHFTIGTANCDKHQAGYCNGPLRAGTTYRIKIRAFTDEDKFTDTVYSS-----PITTERSDT 1253
            :....|.......|| :.....|...|....|..|...:..|.....:.|.     |:.:...|.
 Worm   336 MRISRFEGAKPKADK-RIDSVEGVASAVYKRRKDIARLSGADVRETGIGSGEDGSLPVESSERDW 399

  Fly  1254 VIV------AATVSAVLLVAMVLVVVYCQHRCQLIR-------------------------RASK 1287
            :::      |.||:|:.|||.|.:....:|....|:                         ||||
 Worm   400 LLMPVLFVCAFTVTALGLVAAVQIARSRRHYKDNIQQIAEQLDGKNSFAYQDLCRQRADGGRASK 464

  Fly  1288 LARMQD--ELAALP-----EGYITPNRPVHVKDF-SEHYRI---MSADSDFRFSEEFEELKHVGR 1341
            .:....  |..|:|     .|::..|   .:::: ||..:|   .:...|:| :||..:.|
 Worm   465 SSSTSSWCEETAVPTIDISTGHVVLN---FLQEYLSEPTKIEAQWNGIKDYR-NEERTKTK---- 521

  Fly  1342 DQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSD------YINANYMPGHNSPRE--F 1398
              |..||:      :||  .|||:|.:      :.|.||..      |:||::: ..:.||:  :
 Worm   522 --AEKFAS------QNR--TILPFDDN------IVDIDGKTAENEDFYLNASFI-YDDDPRQAVY 569

  Fly  1399 IVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVAMFYGDIKVQLIIDTH 1463
            |..|.|..|....||:..|:.....:|.|:...|..:||  .||| |..:..:|..::.|:.:
 Worm   570 IAAQTPASSQIAAFWQTIWQHGVCLVVNLSTPEECKQEK--NYWP-DTGSEVHGAFEIHLVSE-- 629

  Fly  1464 YHDWSISEFMVS-------RNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPI 1521
             |.|| .:::|.       :|.::|.:..||:.:|.....|...:|::.|.|............:
 Worm   630 -HIWS-DDYLVRSFYLKNLQNSQTRTITQFHYLSWQKESTPTSAKSILEFRRKVNKSYRGRSSAV 692

  Fly  1522 IVHCSAGVGRSGTFIALD----RILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLL 1582
            :||...|.||:|.:.|:|    |:|:.|.:   :|:...|..:|.:|..||.|..|:..::.|
 Worm   693 LVHSWDGSGRTGVYCAVDVLCARLLRGIRQ---IDVVATVEHLRDQRDGMVATGDQFKLVYGC-- 752

  Fly  1583 AVLEGKEHLL 1592
             |.:...|||
 Worm   753 -VAQEVNHLL 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp4E	NP_525076.2	FN3	<94..>334	CDD:442628
		fn3	247..328	CDD:394996
		FN3	319..>749	CDD:442628
		fn3	708..796	CDD:394996
		fn3	902..978	CDD:394996
		fn3	1013..1092	CDD:394996	21/104 (20%)
		PTP_tm	1127..1247	CDD:465889	28/134 (21%)
		R3-PTPc	1358..1579	CDD:350396	63/239 (26%)
ida-1	NP_498245.2	R-PTP-N-N2	553..758	CDD:350394	57/218 (26%)