Protein Alignment Ptp4E and epha6

DIOPT Version :10

• Sequence 1: NP_525076.2
• Gene: Ptp4E / 31425
• FlyBaseID: FBgn0004368
• Length: 1767
• Species: Drosophila melanogaster
• Sequence 2: XP_005159987.2
• Gene: epha6 / 100005538
• ZFINID: ZDB-GENE-090311-43
• Length: 1005
• Species: Danio rerio
• Alignment Length: 638
• Identity: 123/638 - (19%)
• Similarity: 196/638 - (30%)
• Gaps: 222/638 - (34%)

  Fly   918 LHWTAPAG-------EYTDFELQYLSADEEAPQLLQNV--------TKNTEITLQGLRPYHNYTF 967
            |.|..|:.       .||...|:..:..::......||        ..:|.:.:|....:.||||
Zfish   345 LEWMPPSDTGGRKDISYTALCLRCGADGQDCEPCNSNVRFVPKPTGLTSTSVVVQDFVAHANYTF 409

  Fly   968 TVVVRSGSIQGTDFADVSVSTLMRSSAPISASYQTLTAPPGKVDYFQPSDVQPGEVTFEWSLEPA 1032
            .:...:| :.|       :...||..|.|:.|  |..|.|..|...:........|...|. |..
Zfish   410 QIEALNG-VSG-------LGRSMRQIANITVS--TEQAGPSLVGVVRKDWASQTSVALSWQ-ETE 463

  Fly  1033 EQHGPI-DYFRITCQNADDAADVSSYE-----FPVNATQGK-----IDGLVPGNHYIFRIQAKSA 1086
            :.|..| ||            ::..||     ...::|:.|     :.||.|...|.|.::|::.
Zfish   464 QPHAAILDY------------EIKYYEKEQEQLSYSSTRTKSPSVIVTGLKPSTVYAFHVRARTL 516

  Fly  1087 LGYGAEREHIQTMPILAPPVPEPSVTP-LEVSRTSSTIEISFRQGYFSNAHGMVRSYTIIIAEDV 1150
            .||.                   |.:| .|.:......|.:..||          ...:|:...|
Zfish   517 AGYS-------------------SYSPKFEFATGDEDSEEAVDQG----------QVLVIVTATV 552

  Fly  1151 GKNASGLEMPSWQDVQAYTVWLPYQAIEPYNPFLTSNGS----RKSSLEAEHFTIGTANCDKHQA 1211
            |                     .:..:.....||...|.    .||.:::|         ||.:.
Zfish   553 G---------------------GFSLLVILTLFLLITGRCQWYIKSKIKSE---------DKKRT 587

  Fly  1212 GYCNG--PLRAGTTYRIKIRAFTDED------KFTDTVYSSPITTERSDTVIVAATVSAV----- 1263
            .|.||  |.....||   |...|.||      :|...:..|.|..||   ||.|.....|
Zfish   588 QYQNGHVPFPGLKTY---IDPDTYEDPSQAVHEFAKEIDPSRIRIER---VIGAGEFGEVCSGRL 646

  Fly  1264 -------LLVAM-VLVVVYCQ-HRCQLIRRASKLARMQDELAALPEGYITPNRPVHVKDFSEHYR 1319
                   :.||: .|...|.: .|...:|.||.:.:..:......||.:|.:|||.:  ..|:..
Zfish   647 RIPGKKEIPVAIKTLKGGYTERQRRDFLREASIMGQFDNPNIIHLEGVVTKSRPVMI--VVEYME 709

  Fly  1320 IMSADSDFRFSE--------------------EFEELKHVGRDQACSFANLPCNRPKNRFTNILP 1364
            ..|.||..|..:                    ...::.:|.||.|.              .|||.
Zfish   710 NGSLDSFLRKHDGHFTVIQLVGMLRGIASGMMYLSDIGYVHRDLAA--------------RNILV 760

  Fly  1365 YDH-----SRFKLQPV--DDDDGSDYINANYMPGHNSPREFIVTQGPLH---STREEFW------ 1413
            .|:     |.|.|..|  ||.:.:......:..|...|..:...:...:   |:..:.|
Zfish   761 DDNLVCKVSDFGLSRVLEDDPEAAYTTTVLFCQGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVM 825

  Fly  1414 --------RMCWESNSRAIV---------------------MLTRCFEKGREK 1437
                    |..||.:::.::                     ::..|::|.|.:
Zfish   826 WEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPVALHQLMLLCWQKERSR 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptp4E	NP_525076.2	FN3	<94..>334	CDD:442628
		fn3	247..328	CDD:394996
		FN3	319..>749	CDD:442628
		fn3	708..796	CDD:394996
		fn3	902..978	CDD:394996	15/74 (20%)
		fn3	1013..1092	CDD:394996	19/89 (21%)
		PTP_tm	1127..1247	CDD:465889	25/131 (19%)
		R3-PTPc	1358..1579	CDD:350396	20/125 (16%)
epha6	XP_005159987.2	None