Protein Alignment Torsin and tor2a

DIOPT Version :10

• Sequence 1: NP_572178.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001029352.1
• Gene: tor2a / 559805
• ZFINID: ZDB-GENE-050913-60
• Length: 310
• Species: Danio rerio
• Alignment Length: 311
• Identity: 97/311 - (31%)
• Similarity: 160/311 - (51%)
• Gaps: 12/311 - (3%)

  Fly    29 TIGAVGAVALGAYFK-EHTYCRFAECCDDRNIPARIDELERSLERTLIGQHIVRQHIVPALKAHI 92
            |:..:...:||:.|: :..:|..::.||....| .|..||..|.:.|.|||:.:..:..|:...:
Zfish     4 TLLLIYCTSLGSGFEMKSIFCSISDSCDCDYKP-DIKGLEWDLYKNLYGQHMAQDIVSEAVVNFL 67

  Fly    93 ASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYRVKI 157
            .:.|..| |||:||||..||||:.|:..|...:|.....|.|:.:::....||....|..||..:
Zfish    68 QNENPDR-PLVLSFHGSSGTGKSLVSSMIGRHIYGTAMGSPYIHQFIPTLHFPSADRVLQYRSDL 131

  Fly   158 NNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVDYNAFVDGTDNTKAIFIFLSNTAGSHIAS 222
            ...|..:|.:|.||:|||||::|||.||.|.|...:.....:..|:..|||:||:| :||..|.:
Zfish   132 KRRVEKSLTACARSIFIFDEMEKMPPGVIDVLEPHLGPYHILFQTNYRKAIYIFIS-SAGEEIVN 195

  Fly   223 HLG-SVMKNGRLREDTRLSDFEPLLRKAAY-NMDGGMKKTTMIESHVIDHFIPFLPMEKAHVIKC 285
            .:. ...:.||.||:.:..:.|..:..|.| |.:.|...:.:|...:|..|:||||:.:.||.:|
Zfish   196 RIALESRRAGRDREEIQPDELEDSIADAVYNNKNSGFYHSRIITEKLITRFVPFLPLLRRHVERC 260

  Fly   286 LEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHS-LFAISGCKTLEKKV 335
            .:.||.:     :....:|.:...:..:::|....| .|:.:|||.:..||
Zfish   261 AQRELCQ-----RGECQRKDVASAVGGAMNYTPNDSKYFSSTGCKLVPAKV 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_572178.1	P-loop containing Nucleoside Triphosphate Hydrolases	55..175	CDD:476819	40/119 (34%)
tor2a	NP_001029352.1	P-loop containing Nucleoside Triphosphate Hydrolases	31..149	CDD:476819	40/119 (34%)