Protein Alignment Torsin and Tor3a

DIOPT Version :10

• Sequence 1: NP_572178.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_075630.2
• Gene: Tor3a / 30935
• MGIID: 1353652
• Length: 385
• Species: Mus musculus
• Alignment Length: 324
• Identity: 98/324 - (30%)
• Similarity: 158/324 - (48%)
• Gaps: 28/324 - (8%)

  Fly    20 LPL---QSVDPLTIGAVGAVALGAYFKEHTYCRFAECCD---DRNIPARIDELERSLERTLIGQH 78
            |||   :|:|.||          |:.     |||.:||.   |..|...:..||..|...|.|||
Mouse    77 LPLWGRRSLDVLT----------AWL-----CRFQDCCSGGGDCRISNNLTGLESDLRVRLHGQH 126

  Fly    79 IVRQHIVPALKAHIASGNKSRKPLVISFHGQPGTGKNFVAEQIADAMYLKGSRSNYVTKYLGQAD 143
            :..:.::.|:|.::...... |.|.:||||..||||||:|..:.|.:|..|.||:.|..::....
Mouse   127 LASKLVLRAVKGYLEMPQVG-KALALSFHGWSGTGKNFLARILMDNLYRDGMRSDCVKMFISTFH 190

  Fly   144 FPKESEVSNYRVKINNAVRDTLRSCPRSLFIFDEVDKMPSGVFDQLTSLVD-YNAFVDGTDNTKA 207
            ||....|..|:.::...:::|...|.:|.|:|||.:|:..|:.:.|...:: .:....|.:..:|
Mouse   191 FPHPKYVDTYKEELQRQMQETQWRCHQSTFVFDEAEKLHPGLLELLEPYLEPRSPEARGVEAPRA 255

  Fly   208 IFIFLSNTAGSHIASHLGSVMKNGRLREDTRLSDFE-PLLRKAAYNMDGGMKKTTMIESHVIDHF 271
            ||:||||..||.|...:.|::|.|..||:......| ||..:.....|.....:.:::.|:||||
Mouse   256 IFLFLSNLGGSVINEVVLSLLKAGWSREEITTQHLEVPLQAEIMEAADSSFGSSGLLKKHLIDHF 320

  Fly   272 IPFLPMEKAHVIKCLEAELLRWRRDPKQANNQKIIEDIINSSISYDRTHSLFAISGCKTLEKKV 335
            |||||:|..||..|:....|    .......::.:::|............||:..|||::.:::
Mouse   321 IPFLPLEYCHVRLCVRDAFL----GQDLPYTEETLDEIAKMMTYVPEEERLFSSQGCKSISQRI 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_572178.1	P-loop containing Nucleoside Triphosphate Hydrolases	55..175	CDD:476819	38/122 (31%)
Tor3a	NP_075630.2	Torsin	103..222	CDD:399367	38/119 (32%)