Protein Alignment Torsin and tor-2

DIOPT Version :10

• Sequence 1: NP_572178.1
• Gene: Torsin / 31399
• FlyBaseID: FBgn0025615
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_502683.2
• Gene: tor-2 / 189606
• WormBaseID: WBGene00006598
• Length: 310
• Species: Caenorhabditis elegans
• Alignment Length: 293
• Identity: 102/293 - (34%)
• Similarity: 166/293 - (56%)
• Gaps: 5/293 - (1%)

  Fly    48 CRFAECCDDRNIPARIDELERSLERTLIGQHIVRQHIVPALKAHIASGNKSRKPLVISFHGQPGT 112
            |.|..||.:.:| .....|.:..:..:.|||::.:.:|.::|:| .....|:||||:||||..||
 Worm     5 CLFYTCCGETDI-FNYHALYKDFDNKIFGQHLMAESVVHSIKSH-WHNEHSQKPLVLSFHGGTGT 67

  Fly   113 GKNFVAEQIADAMYLKGSRSNYVTKYLGQADFPKESEVSNYRVKINNAVRDTLRSCPRSLFIFDE 177
            |||:|.|.|.:..|..|..|.:|..::...:||.:..:.:|::::.:.:..:.|.|.||:|||||
 Worm    68 GKNYVTEIIVNNTYRSGMHSPFVNYFVATNNFPNKKYIEDYKLELKDQLIRSARRCQRSIFIFDE 132

  Fly   178 VDKMPSGVFDQLTSLVDYNAFVDGTDNTKAIFIFLSNTAGSHIASHLGSVMKNGRLREDTRLSDF 242
            .||:.|.:...:...:||...|.|.|..|.|||||||.....||:......:||::|....|..|
 Worm   133 TDKLQSELIQVIKPFLDYYPAVFGVDFRKTIFIFLSNKGSKEIANIALEHHENGKIRSQLELKHF 197

  Fly   243 EPLLRKAAYNMDGGMKKTTMIESHVIDHFIPFLPMEKAHVIKCLEAEL-LRWRRDPKQANNQKII 306
            |..|..:|:|.:||::.|.||.:.:|||||||||:.|.:|.:|::..| .|.|.|  .|.:.:.:
 Worm   198 ERTLMLSAFNEEGGLRNTDMISNQLIDHFIPFLPLSKFYVSQCIQVHLRKRGRHD--LAKDGEFM 260

  Fly   307 EDIINSSISYDRTHSLFAISGCKTLEKKVAMAI 339
            :.:::|...:..:..:|:.||||.:..|..:.|
 Worm   261 QRVLDSLEFFPESSKIFSSSGCKRVNAKTDLEI 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Torsin	NP_572178.1	P-loop containing Nucleoside Triphosphate Hydrolases	55..175	CDD:476819	37/119 (31%)
tor-2	NP_502683.2	Torsin	12..130	CDD:399367	37/119 (31%)
		ClpA	<157..234	CDD:440308	34/76 (45%)