Protein Alignment Cmtr1 and cmtr1

DIOPT Version :10

• Sequence 1: NP_572148.2
• Gene: Cmtr1 / 31355
• FlyBaseID: FBgn0029693
• Length: 788
• Species: Drosophila melanogaster
• Sequence 2: NP_956427.1
• Gene: cmtr1 / 393102
• ZFINID: ZDB-GENE-040426-696
• Length: 829
• Species: Danio rerio
• Alignment Length: 805
• Identity: 322/805 - (40%)
• Similarity: 468/805 - (58%)
• Gaps: 65/805 - (8%)

  Fly     4 PSDDENS-------EPTPKKIKREWVKSYSNKAMEMMKKMGYENDKGLGKSNQGRLEPIIAVQQD 61
            |||.:||       |.:.|      ...|:|.:.::|.|||:...:||||..|||.|.:.|..|.
Zfish    57 PSDSQNSQGSMAHNEASNK------FAMYNNVSQKLMAKMGFREGEGLGKYGQGRKEIVEASTQR 115

  Fly    62 GRRGFGLKLDTVQSSAG-QWDPACEELEIPEPVLWLHNPGSRADAYSLDQLMGHLVTGEKKLTLD 125
            ||||.||.|...|.... .|:...|...| |.|.|.  |.|..:....|:|...:..|||||.:|
Zfish   116 GRRGLGLMLKGFQGDLNVDWEDEPEPSAI-EQVSWF--PESSPEIPDSDELRDWMTIGEKKLKID 177

  Fly   126 GETRYCDPAILHHILNAKTVFDDLNDNEKRRARSRCNPFETIRSSIFLNRAAVKMANIDSMCNFM 190
            .|..:|...:||.:|..|||||||...|.||||:|.||:||||.:.||||||:||||:|.:.::|
Zfish   178 DEIEFCSENLLHLLLRCKTVFDDLEGEEMRRARTRSNPYETIRGAFFLNRAAMKMANMDHVFDYM 242

  Fly   191 FTNPRDPAGQTLV--APDELLYFTDMCAGPGGFSEYVLYRKSWEAKGFGFTLRGANDFKLEKFFA 253
            ||||:|..|:.|.  ...|||||.|:||||||||||||:|:.|.|||||.||:||||||||.|:|
Zfish   243 FTNPKDSQGKVLTRDKEGELLYFGDVCAGPGGFSEYVLWRRRWHAKGFGMTLKGANDFKLEDFYA 307

  Fly   254 ASPESFDTFY---GVKEDGNIFDESNQDSLNEYIRMHTP-QGVHFAMADGGFSVEGQKNIQEILS 314
            |..|.|:.:|   |:..||:|....|..:...::...|. :|:||.|||||||||||:|:|||||
Zfish   308 APSELFEAYYGEGGIDGDGDITRPENISAFRNFVLDSTEGRGLHFLMADGGFSVEGQENLQEILS 372

  Fly   315 KQLYLCQFLTALKILRPNGSFVCKVFDLFTPFSVGLVYLMYKCFQQIAIIKPNSSRPANSERYLV 379
            |||.||||||||.::||.|.|:||.|||||||||||:||:|.||:::::.||.:|||||||||:|
Zfish   373 KQLLLCQFLTALSVVRPGGHFLCKTFDLFTPFSVGLIYLLYLCFERVSLFKPVTSRPANSERYVV 437

  Fly   380 CKYKRSDAETAGIVAYLNTVNLMLSDESQLDENDVLEIFNANELAEDEDFLRYIIDSNNAIGKKQ 444
            ||..:..  |..:..|:.|:||.| ::.:..:.||:|:...:.:..|.||.:|:|.||.:....|
Zfish   438 CKGLKPG--TDAVREYMFTINLKL-NQFRHSDRDVIEVVPLDIIKGDTDFFQYMIGSNESYCAVQ 499

  Fly   445 IVGLRKIAAFAQNLELKETKQSEVRQECLKRWGLPDKLRQAPE-NKPTDRLLDELLADWANERSW 508
            |..|.||.|:.::..|.|.:|:::|:||||.||:|||.|..|. :.|.::..:  |...:...|:
Zfish   500 IKALAKIHAYVRDTTLFEARQADIRKECLKLWGIPDKARVTPSTSDPKNKFYE--LVKGSEMDSF 562

  Fly   509 LSLPATEMKGVASLNAT----IKNVADWYFVPVGREETNINACSLFLCKSRGNLLRYT----EHK 565
            .|.|       .:||:.    :::|.|:..:..|.|:       |||. :.|....||    ...
Zfish   563 NSRP-------TALNSVNLEKLQHVLDYRCIVGGGEQ-------LFLL-ALGRSQIYTWDGKAPS 612

  Fly   566 KWELVETAFEVQ-PRSIFFG-QIVYEFYGEGRTIQRMAALHIIDGICLGGVDIRRRPYRERVSMC 628
            :|:.:|. |::: ||..... :||.|..|||:..:|:.|:|::|.:.|.|.|:|.:.:.:|:.|.
Zfish   613 RWKKLEN-FKMELPRDTLLSVEIVQELKGEGKAQRRINAVHVLDALVLNGTDVRDQHFNQRIQMV 676

  Fly   629 DKFARSLNKPYRKDRTFGALRSKPLFRLQDMGSFFANMRHYVLKDNS--QRLGFALDDNKFFVPG 691
            :||.::::||.|.|  ...:|.|.::||::|...|..:...:.|.:.  .||.:...|::.|:|.
Zfish   677 EKFVKAVSKPSRPD--MNPIRVKEVYRLEEMEKIFVRLEMKITKSSGGMPRLSYTGRDDRHFLPT 739

  Fly   692 GIMMFCELTNNYVSAHSRSRGQLYYFNVRNKESYYKDQIPRNKADEIFASFRFSFSCRLLWKWTD 756
            |:.:...:.:.:..|.|:|..:.:::|.:.|||.|  .:|....    |.|......||.|.|.:
Zfish   740 GLYIIKTVNDPWTMAFSKSSKRKFFYNKQTKESTY--DLPATSV----APFYVCHQDRLFWAWEE 798

  Fly   757 LRQVEELATEDNPKILFRSDFVKFI 781
            ..:|.:..|..||..|.:.|.|.||
Zfish   799 GVRVHDSQTRINPDKLSKDDVVSFI 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cmtr1	NP_572148.2	G-patch	25..69	CDD:396249	21/43 (49%)
		FtsJ	172..383	CDD:426399	133/216 (62%)
cmtr1	NP_956427.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..68		5/10 (50%)
		Bipartite nuclear localization signal. /evidence=ECO:0000255|PROSITE-ProRule:PRU00768	2..16
		G-patch	79..121	CDD:396249	20/41 (49%)
		FtsJ	224..440	CDD:426399	132/215 (61%)
		Adenylation_DNA_ligase_like	547..709	CDD:448381	48/181 (27%)
		WW	746..778	CDD:197736	8/33 (24%)