Protein Alignment CG2930 and slc15a1a

DIOPT Version :10

• Sequence 1: NP_001284845.1
• Gene: CG2930 / 31341
• FlyBaseID: FBgn0028491
• Length: 815
• Species: Drosophila melanogaster
• Sequence 2: XP_073768479.1
• Gene: slc15a1a / 100004272
• ZFINID: ZDB-GENE-091204-9
• Length: 743
• Species: Danio rerio
• Alignment Length: 753
• Identity: 299/753 - (39%)
• Similarity: 438/753 - (58%)
• Gaps: 72/753 - (9%)

  Fly   117 VSETEGQQKKLP----YPKSVFFIISNEFCERFNYYGMRTVLVLYLSRVLGYSDDTATVVFHIFT 177
            :.||:.::||..    ||.|:|||:.|||||||:|||||.|||||....|.:.||.||.::|.|.
Zfish     6 MDETKKKKKKTAECCGYPISIFFIVVNEFCERFSYYGMRAVLVLYFRYFLLWDDDLATSIYHAFV 70

  Fly   178 MFVYFLCVFGAIISDSWLGKFKTILYLSLVYICGSVLLTLGAI----------GPLNLPME-TFT 231
            ...|...:.||||:||||||||||:|||:||..|.|::.:..|          .|.|..:. ..:
Zfish    71 ALCYLTPILGAIIADSWLGKFKTIIYLSIVYAVGQVVMAVSTIHDITDANRDGTPDNFTLHIALS 135

  Fly   232 MLGLALIALGSGGIKPCVSAFGGDQFKVPEQVKQITSFFSLFYFSINAGSLISTTVTPILR-EDV 295
            ||||.|||||:|||||||:|||||||: ..|.:|:.:|||:||..||||||:||.:||:|| ::.
Zfish   136 MLGLVLIALGTGGIKPCVAAFGGDQFQ-EHQSRQLNTFFSVFYLCINAGSLLSTLITPVLRAQEC 199

  Fly   296 SCFDDINCYPLAFGVPAVLMIVSVIIFVLGRSLYKMKPPAGNMVVLVSSTIWTALTTKCKEKKT- 359
            .......||||||||||.||:||:::|:.|..:|....|.||::..|...||.||..:.:.:..
Zfish   200 GIHTQQQCYPLAFGVPAALMVVSLVVFIAGSGMYTKTAPEGNIMGSVCKCIWFALNNRFRHRSDI 264

  Fly   360 -NPREHWLDYADKKYDRQLIDDVKVLMRVLFLYLPLPVFWALFDQQGSRWTFQATRMDGDMGSWD 423
             ..||||:|:|::|||:.||..:|::::|||||:|||:||.||||:|||||.|||.|.||.|.:.
Zfish   265 YPKREHWMDWAEEKYDKLLIAQIKMVLKVLFLYIPLPMFWTLFDQKGSRWTLQATTMTGDFGGFV 329

  Fly   424 IKPDQLQVLNPLLILIFIPLYDVALYPALKLVGIR-RPLQKLTMGGILAGIAFIISGVVELSLEK 487
            ::|||:|.:||:|||..:|:.|..::|.:|..|:. .||:::|:|.:.|..|||.:.:|::.::|
Zfish   330 LQPDQMQTVNPILILTLVPIMDRIIFPLIKKCGLNFSPLKRMTVGMLFAATAFIAAALVQMEIDK 394

  Fly   488 TYPDLPYSQNIQLRIFNADNCDYFFTSNIPGAENVTVTSLNA-YTNKDIYAPG------SLDVEF 545
            |.|:.|.|...||::.|..:.....|  :|..|.:.:.|... :|:|...|..      |..|.|
Zfish   395 TLPNFPSSSESQLKVVNMHSESLIVT--VPSQEPLLIGSFEVQHTSKHTTAVSHWCFTISSHVVF 457

  Fly   546 SLSSA------SEACTISADKIPKV-----LTDNTAWSLFLNPLNGSGYYWEEDFVDKPSQSHPL 599
            ..||.      .:...::.:..|::     |...:..:|.: |...:..|.:||...||.:....
Zfish   458 PQSSPDYITFDQQDIRLAFNTTPEINKDLSLIKGSRQTLII-PSEPAEMYLKEDIKSKPKEGKNA 521

  Fly   600 IR---------NVANVPQELSIRWEKASTGEVVYDDLASKTLLTRVNSAEYVVMVGERNVGTFDV 655
            :|         |:.|:  |.|::..:.|...:|...:...||...:.|.|:     .|..|
Zfish   522 VRFVNGWTAYLNITNL--ESSLQPSETSNYTLVSQGMRKFTLTDGIQSCEF-----SRKFG---- 575

  Fly   656 HTGGVYTLLIKDNNNIYEANLEEV-----TSPNSVKILWLVPQYVVMTLGEVMFSVTGLEFSYAQ 715
             .|..||.||.  ::::..:.|.:     ..||||.:...:|||.::|.||||||||||:|||:|
Zfish   576 -FGSSYTFLIP--SDLFSTDCESIKEIEDMQPNSVHMALQIPQYFLITTGEVMFSVTGLQFSYSQ 637

  Fly   716 APPSMKSVLQACWLLTVAFGNVIVVVIAEAALFESQASEFFLFAGLMFADMLIFMVMAYYYVPND 780
            ||.:|||||||.||.|.|.||:||:::||......|.:|:.|||.|:.|..:||.:|||:|...|
Zfish   638 APKNMKSVLQAGWLCTNAVGNIIVLIVAELGKLPKQWAEYVLFASLLVAVSIIFSIMAYFYTYID 702

  Fly   781 PNKVEE---AQPLTAGDAKTEIPALEGGVENKGKDINE 815
            |.::|.   .|..|..|.|.:...||...:...::|.:
Zfish   703 PAEIEAEILKQQETDPDKKKKKETLEMEEKENEQEIKQ 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2930	NP_001284845.1	rad23	<15..>83	CDD:273167
		2A1704	145..776	CDD:273343	272/677 (40%)
slc15a1a	XP_073768479.1	None