DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2901 and VTC2

DIOPT Version :9

Sequence 1:	NP_570077.1	Gene:	CG2901 / 31338	FlyBaseID:	FBgn0029679	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_116651.1	Gene:	VTC2 / 850544	SGDID:	S000001890	Length:	828	Species:	Saccharomyces cerevisiae

Alignment Length:	163	Identity:	39/163 - (23%)
Similarity:	63/163 - (38%)	Gaps:	34/163 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTYESHLTIEWRQQYMRYGDLKELIKQ-----GVENAPSPLTSSDYEVQAYYKAFEETFLT 60
            |.||....:.:...|:..|:.|..||:.:|:     |..:..:....||          |..|:.
Yeast     1 MLFGVKLANEVYPPWKGSYINYEGLKKFLKEDSVKDGSNDKKARWDDSD----------ESKFVE 55

  Fly    61 ECQSELTGVNNFFLEKLLEARRKHGHLKLQLLAYSREPGHTGSDSSLSQRAERSQKKLMTTRQLR 125
            |...||..|..|.|:|......:..||:.|          |.:::::         |.:.....:
Yeast    56 ELDKELEKVYGFQLKKYNNLMERLSHLEKQ----------TDTEAAI---------KALDADAFQ 101

  Fly   126 YAYAEFYLSLVLIQNYQSLNETGFRKICKKYDK 158
            ....|.......:.|::.||.|||.||.||:||
Yeast   102 RVLEELLSESTELDNFKRLNFTGFAKIVKKHDK 134

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2901	NP_570077.1	COG5408	1..162	CDD:227695	39/163 (24%)
		SPX_XPR1_like	2..158	CDD:269898	36/160 (23%)
		EXS	260..597	CDD:281164
VTC2	NP_116651.1	COG5036	1..555	CDD:227369	39/163 (24%)
VTC2	NP_116651.1	VTC1	662..791	CDD:227589
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343545
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.569298	Normalized mean entropy	S1995
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.790