DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2901 and AT1G35350

DIOPT Version :9

Sequence 1:	NP_570077.1	Gene:	CG2901 / 31338	FlyBaseID:	FBgn0029679	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_174768.2	Gene:	AT1G35350 / 840424	AraportID:	AT1G35350	Length:	751	Species:	Arabidopsis thaliana

Alignment Length:	775	Identity:	198/775 - (25%)
Similarity:	318/775 - (41%)	Gaps:	200/775 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTYESHLTIEWRQQYMRYGDLKELIK-----------QGVEN------------------- 35
            |||||.|.:.:..||:|.||.|..||.:::           |||..
plant     1 MKFGKEYVAQMIPEWQQAYMDYTCLKTILREIKTSQKRSESQGVLKRKLSGRRNFSGLTKRYSRT 65

  Fly    36 -APSPLTSSDYEVQAY-----YKAFEETFLTEC----QSELT----------GVNNFFLEKLLEA 80
             :...|.:.|..|.|.     ::.:|.|.|...    :|||.          .||.|:...:.|.
plant    66 FSSRDLENHDIMVHATTGDDGFEKYETTILKVSEVGRESELVFFKTLDLEFDKVNRFYRSNVEEL 130

  Fly    81 RRKHGHLKLQ---LLAY--------------------------SREPGHT--------------- 101
            .::...|..|   |:||                          ..:.|.|
plant   131 VKEAVVLNRQMDALIAYRIKLDQPSTSWSCSETVSVDINALDSKEQKGKTLAEEMGIKVEENVSN 195

  Fly   102 GSDSSLSQ-----------RAERSQKKLMTT------------------------RQLRYAYAEF 131
            |.||:...           |..::|:..::|                        .:|:..:.||
plant   196 GGDSTKETAPEALSVLDRIRLNKNQENPLSTIRNVLKLSNKEDIKFTKENLKKIEERLKNVFIEF 260

  Fly   132 YLSLVLIQNYQSLNETGFRKICKKYDK-NMRSVAAGRWFVENVLDAPFTDVRLLQRMTIEVEDLY 195
            |..|..::||..||.....||.||||| .:|:  |.:.::|.|..:..|....:.::.:.||.::
plant   261 YRKLRHLKNYSFLNTLAISKIMKKYDKIALRN--AAKLYMEMVDKSYLTSSDEINKLMLRVESIF 323

  Fly   196 TTHLANGDRSLAMEKLRVPPLGEPTPPSMVFRAGIALGMLIMLLVATAISYWKRAPLEDHTPGLM 260
            ..|.|..:||..|..||  |........:.|..|..:|..:.|::|..:..        |...:|
plant   324 VEHFAGSNRSKGMNLLR--PKVTKEKHRITFSTGFFVGCTVSLVIALGLFI--------HARNIM 378

  Fly   261 -----RLFR-------GPFTWVIFNFYM-AANVAGWQQAGVNHILIFEIDPRSHLQPATFLEIAC 312
                 :|:.       ..|.:|:.:..| |:|:..|::..||:..||.....:.|.....|.:
plant   379 GAVGHKLYMETMFPLYSLFAFVVLHMIMYASNIYFWKRYRVNYPFIFGFKEGTELGYGHVLLL-- 441

  Fly   313 TFGILWALSMLGFLYN-DLIGVSDP---------YVFPLGLILIMVGLLVVPLPIMNWPARWWTI 367
            :|| |..|::...|.| |:  ..||         .:.||.::.:::.:.|.|..|....:|::.:
plant   442 SFG-LGTLALCAVLVNMDM--EMDPNTNDYKTITELVPLFVVALVIAISVCPFNIFYRSSRFFFL 503

  Fly   368 KLVGRVITAPLHYVGFADFWMGDQMNSLVSCIVDHYYTVRFYAISWLRY-DRVNNCFEPDVMVP- 430
            .::.|.|.|||:.|...||::.||:.|.|..:....:.:.:|  .|..: .|.:.|...||...
plant   504 MVLFRCIAAPLYKVNLPDFFLADQLTSQVQALRSLEFYICYY--GWGDFKQRQSTCKSSDVYSTF 566

  Fly   431 --ITMCLPGWFRFAQCLRRFRDSGSKSMSYLINAGKYSTTFLVVLFST---LRRNSEGGYANTFS 490
              |...:|.|.||.||:||..:  .|.:|...||.||..|.:.|...|   :.|.::...|
plant   567 YFIVAVIPYWSRFLQCVRRLIE--EKDVSQGFNALKYLLTIVAVCLRTAFSINRGNDWKIA---- 625

  Fly   491 NPYTWLFLSSCVVATIYCYLWDVIRDFGLFRIMRGERIFLRKQLVYP-QAFYYFVIVENLVLRLF 554
               .|:|..   :||.|...||::.|:||  :.|..:.:||::|:.| ::.||..:|.|:||||.
plant   626 ---AWVFSG---LATFYGTYWDIVYDWGL--LHRPSKSWLREKLLVPHKSVYYVAMVVNVVLRLA 682

  Fly   555 W---AVEFTILYHNLMTPYNMRTISSILEITRRFIWNYVRLENEHLFNCGNFRATRDIHL 611
            |   .::|.|.:.:..|   |..:.:||||.||.|||:.|||||||.|.|.|||.:.:.|
plant   683 WLQTVLDFNISFLHRET---MVALIAILEIIRRGIWNFFRLENEHLNNVGKFRAFKSVPL 739

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2901	NP_570077.1	COG5408	1..162	CDD:227695	60/290 (21%)
		SPX_XPR1_like	2..158	CDD:269898	57/284 (20%)
		EXS	260..597	CDD:281164	109/370 (29%)
AT1G35350	NP_174768.2	SPX_PHO1_like	2..295	CDD:269897	61/294 (21%)
		SPX	3..300	CDD:281146	60/298 (20%)
		EXS	391..725	CDD:281164	107/357 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.940