DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2901 and AT1G26730

DIOPT Version :9

Sequence 1:	NP_570077.1	Gene:	CG2901 / 31338	FlyBaseID:	FBgn0029679	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_173995.1	Gene:	AT1G26730 / 839214	AraportID:	AT1G26730	Length:	750	Species:	Arabidopsis thaliana

Alignment Length:	761	Identity:	198/761 - (26%)
Similarity:	316/761 - (41%)	Gaps:	173/761 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTYESHLTIEWRQQYMRYGDLKELIKQ-------------------GVENAPSPLT----- 41
            |||||.:...:..||:|.||.|..||.::::                   |..|. |.||
plant     1 MKFGKDFVRQMIPEWQQAYMDYAGLKSILQEIQTSRKRSERPGILKRKLSGSRNF-SGLTKRYSR 64

  Fly    42 ---SSDYEVQAY----------YKAFEETFLTECQS--------------ELTGVNNFFLEKLLE 79
               :.:.|:|..          ::.:|.|.|...::              |...||:|:..|:.|
plant    65 TASTREPEIQDILVHATTGDDGFERYETTILEVAEAGRESELAFFKTLDLEFDKVNHFYRSKVEE 129

  Fly    80 ARRKHGHLKLQ---LLAYS---REP-------------------------------------GHT 101
            ..::...|..|   |:|:.   ..|                                     |..
plant   130 MVKEAVVLNKQMDALIAFRIKVERPSSSWSCSETVSVDMNALDSNDQRNTLAEEMGIRVEGNGSN 194

  Fly   102 GSDSS---------------LSQRAE------------RSQKKLMTTRQ--------LRYAYAEF 131
            |.||:               |::..|            .:|::|..||:        |:..:.||
plant   195 GGDSTKESVPQVLSVLERIRLNKTQETPLSTIKNVLKLSNQEELKFTRENLKKIEERLKNVFIEF 259

  Fly   132 YLSLVLIQNYQSLNETGFRKICKKYDKNMRSVAAGRWFVENVLDAPFTDVRLLQRMTIEVEDLYT 196
            |..|..::||..||.....||.||||| :.|.:|.:.::|.|..:..|....:.::.:.||..:.
plant   260 YRKLRHLKNYSFLNTLAISKIMKKYDK-IASRSAAKPYMEMVDKSYLTSSDEINKLMLRVESTFV 323

  Fly   197 THLANGDRSLAMEKLRVPPLGEPTPPSMVFRAGIALGMLIMLLVATAISYWKRAPL--EDHTPGL 259
            .|.|..:||..|..||  |..:.....:.|..|..:|..:.|:||..:....|..:  ..|...:
plant   324 EHFAGLNRSKGMNLLR--PKVKKEKHRITFSTGFFVGCTVSLVVALVMFIHARNIMGAVGHKVYM 386

  Fly   260 MRLFRGP----FTWVIFNFYM-AANVAGWQQAGVNHILIFEIDPRSHLQPATFLEIACTFGILWA 319
            ..:|  |    |.:|:.:..| |:|:..|::..||:..||.....:.|.....|.::...|.|..
plant   387 ETMF--PLYSLFAFVVLHMIMYASNIYFWKRYRVNYPFIFGFKEGTELGYRHVLLLSFGLGTLAL 449

  Fly   320 LSMLGFLYNDLIGVSDPY-----VFPLGLILIMVGLLVVPLPIMNWPARWWTIKLVGRVITAPLH 379
            .::|..|..::...::.|     :.|:.::.::|.:|..|..|....:|.:.:.:|.|.|.|||:
plant   450 CAVLINLDMEMDPNTNDYKTMTELLPMFILALVVAILFCPFNIFYRSSRVFFLMVVFRCIAAPLY 514

  Fly   380 YVGFADFWMGDQMNSLVSCIVDHYYTVRFYAISWLRYDRVNNCFEPDVMVP---ITMCLPGWFRF 441
            .|...||::.||:.|.|..:....:.:.:|.....:: |.|.|...||...   |...:|.|.||
plant   515 KVNLPDFFLADQLTSQVQALRSLEFYICYYGWGDFKH-RQNTCRSSDVYSTFYFIVAVIPYWSRF 578

  Fly   442 AQCLRRFRDSGSKSMSYLINAGKYSTTFLVVLFSTLRRNSEGGYANTFSNPY---TWLFLSSCVV 503
            .||:||..:....|..|  ||.||..|.:.|...|       .|:....|.:   .|:|   ..:
plant   579 LQCVRRLIEENDSSQGY--NALKYLLTVVAVCLRT-------AYSFNRGNIWKISAWVF---SAL 631

  Fly   504 ATIYCYLWDVIRDFGLFRIMRGERIFLRKQLVYP-QAFYYFVIVENLVLRLFWAVEFTILYHNL- 566
            ||.|...||::.|:||  :.|..:..||::|:.| :|.||..||.|:|||:.|..  |:|..||
plant   632 ATFYGTYWDIVFDWGL--LHRPSKHLLREKLLVPHKAVYYVAIVLNIVLRMAWLQ--TVLDFNLS 692

  Fly   567 -MTPYNMRTISSILEITRRFIWNYVRLENEHLFNCGNFRATRDIHL 611
             :....|..:.:.|||.||.|||:.|||||||.|.|.|||.:.:.|
plant   693 FLHRETMIALLAALEIIRRGIWNFFRLENEHLNNVGKFRAFKSVPL 738

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2901	NP_570077.1	COG5408	1..162	CDD:227695	60/289 (21%)
		SPX_XPR1_like	2..158	CDD:269898	57/284 (20%)
		EXS	260..597	CDD:281164	107/355 (30%)
AT1G26730	NP_173995.1	SPX_PHO1_like	2..294	CDD:269897	61/293 (21%)
		SPX	3..299	CDD:281146	60/297 (20%)
		SPX	<212..286	CDD:271919	20/73 (27%)
		EXS	390..724	CDD:281164	107/352 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940