Protein Alignment CG2901 and xpr1

DIOPT Version :10

• Sequence 1: NP_570077.1
• Gene: CG2901 / 31338
• FlyBaseID: FBgn0029679
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001016753.1
• Gene: xpr1 / 549507
• XenbaseID: XB-GENE-1015946
• Length: 692
• Species: Xenopus tropicalis
• Alignment Length: 677
• Identity: 272/677 - (40%)
• Similarity: 393/677 - (58%)
• Gaps: 62/677 - (9%)

  Fly     1 MKFGKTYESHLTIEWRQQYMRYGDLKELIKQGVENAPSPLTSSDYEVQAYYKAFEETFLTECQSE 65
            |||.:...:|:|.|||:||::|...||::....:.|||...:.:..|:.||..|||.|...|:.|
 Frog     1 MKFAEHLSAHITPEWRKQYIQYEAFKEMLYAAQDQAPSIEVTDEDTVKRYYAKFEEIFFQTCEKE 65

  Fly    66 LTGVNNFFLEKLLEARRKHGHLKLQL---LAYSRE----PGHTGSDSSLSQR---------AERS 114
            |..:|.|:.|||.||:|:...|:.:|   |...||    ||       |.||         .||.
 Frog    66 LAKINTFYSEKLAEAQRRSATLQNELQSSLDAQRESSAIPG-------LRQRRKAVFALTHEERV 123

  Fly   115 QKKLMTTRQLRYAYAEFYLSLVLIQNYQSLNETGFRKICKKYDKNMRSVAAGRWFVENVLDAPFT 179
            |.:  ..:.|:.|::||||||:|:||||:||.||||||.||:||.:.:.....|.|.:|..|||.
 Frog   124 QHR--NIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHVEVAPFY 186

  Fly   180 DVRLLQRMTIEVEDLYTTHLANGDRSLAMEKLRVPPLG--EPTPPSMVFRAGIALGMLIMLLVAT 242
            ..:.:.::..|.|.:.|..|.:|||..||::|||||||  :|.|....||.|:..|:.|:|.:|.
 Frog   187 TCKKINQLISETETVVTNELESGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLYCGIFIVLNMAI 251

  Fly   243 AISYWKRAPLEDHTPGLMRLFRGPFTWVIFNFYMAANVAGWQQAGVNHILIFEIDPRSHLQPATF 307
            .::.......:|..| ::|::||.|..:.|.|.:..|..||:||||||:||||::||::|.....
 Frog   252 IMAGSHYLLGKDVWP-MVRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRNNLSHQHL 315

  Fly   308 LEIACTFGILWALSMLGFLYNDLIGVSDPYVFPLGLILIMVGLLVVPLPIMNWPARWWTIKLVGR 372
            .|||...||||..|:...::...|.: ..::.||.|..:|:..||.|.....:.:|:|.:||:.|
 Frog   316 FEIAGFLGILWCFSLFSCIFGLWINL-QMHLNPLILYGLMLLFLVNPTKTFYYKSRFWLLKLLFR 379

  Fly   373 VITAPLHYVGFADFWMGDQMNSLVSCIVDHYYTVRFYA--ISWLRYD-------RVNNCFEPDVM 428
            |.|||.|.|||||||:.||:|||...::|..:.:.||:  :.|...|       .|.|.:...|.
 Frog   380 VFTAPFHKVGFADFWLADQLNSLAVILMDLEFMICFYSFELKWGDSDGLVNSANSVCNSYSYGVR 444

  Fly   429 VPITMCLPGWFRFAQCLRRFRDSGSKSMSYLINAGKYSTTFLVVLFSTL------RRNSEGGYAN 487
            . :..|:|.|.||.|||||:||: .::..:|:|||||||||.:|.|:.|      |.:|:   |.
 Frog   445 A-VVQCIPAWLRFIQCLRRYRDT-KRAFPHLVNAGKYSTTFFMVTFAALYSTHKERNHSD---AQ 504

  Fly   488 TFSNPYTWL---FLSSCVVATIYCYLWDVIRDFGLFRIMRGERIFLRKQLVYPQ-AFYYFVIVEN 548
            .|.  |.|:   .:|||     |..:||:..|:|||....||..|||:::|||| |:||..|:::
 Frog   505 VFF--YLWIIFYLISSC-----YTLIWDLKMDWGLFDRNAGENTFLREEIVYPQKAYYYCAIIQD 562

  Fly   549 LVLRLFWAVEFTILYHNLMTPYN--MRTISSILEITRRFIWNYVRLENEHLFNCGNFRATRDIHL 611
            ::||..|.::.::...||.|...  :.|:.:.||:.|||:||:.|||||||.|||.|||.|||.:
 Frog   563 VILRFAWTIQISVTSLNLFTDAGDIISTVLAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISV 627

  Fly   612 AALNPRQERMLESMMDESDGVSNRRKS 638
            |.||...:.:||.|||:.|||.||.||
 Frog   628 APLNADDQTLLEQMMDQDDGVKNRVKS 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2901	NP_570077.1	SPX_XPR1_like	2..158	CDD:269898	69/171 (40%)
		EXS	259..597	CDD:460816	141/358 (39%)
xpr1	NP_001016753.1	SPX_XPR1_like	2..165	CDD:269898	69/171 (40%)
		Important for inositol polyphosphate binding. /evidence=ECO:0000250|UniProtKB:P43585	158..165		4/6 (67%)
		EXS	267..613	CDD:460816	141/358 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	660..692