Protein Alignment CG2901 and spx2

DIOPT Version :10

• Sequence 1: NP_570077.1
• Gene: CG2901 / 31338
• FlyBaseID: FBgn0029679
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_588554.2
• Gene: spx2 / 3361154
• PomBaseID: SPCC1827.07C
• Length: 682
• Species: Schizosaccharomyces pombe
• Alignment Length: 708
• Identity: 186/708 - (26%)
• Similarity: 300/708 - (42%)
• Gaps: 111/708 - (15%)

  Fly     1 MKFGKTYESHLTIEWRQQYMRYGDLKELIKQGVENAPSP--------LTSSDYE-------VQAY 50
            |||||..|.....||...|..|...|::| .|:...||.        |..:..|       :..:
pombe     1 MKFGKVIEGQSVAEWASAYFDYKKGKKII-AGIAKNPSEGLYGTSGILGETPEEAIVKRGQIHRF 64

  Fly    51 YKAFEETFLTECQSELTGVNNFFLEKLLEARRKHGHLKLQ------LLAYSREPGHTGS------ 103
            :..|:| ||.:   :...|..||...:.:||.:...:..|      |.|:.:....:||
pombe    65 HPLFQE-FLDQ---QANKVEEFFENLVSDARERMDLISDQVDIYEKLRAFKKGTLESGSVVLIQK 125

  Fly   104 -DSSLSQRAER----------------------------SQKKLMTTRQLRYAYAEFYLSLVLIQ 139
             .|.|.||.:.                            |.:||.:  :|:....:||..|.|:.
pombe   126 QHSKLRQRLDSILNFSRLQPAYHIPARKSVPTDAYTPMVSYRKLKS--KLKTTLLDFYDYLKLVS 188

  Fly   140 NYQSLNETGFRKICKKYDKNMRSVAAGRWFVENVLDAPFTDVRLLQRMTIEVEDLYTTHLANGDR 204
            .||.||:..||||.|||||.:.:...|.| |:.:....|||..:.....:.|||:|.....|.::
pombe   189 QYQHLNQQAFRKIVKKYDKTLHTDLQGFW-VDYMSRYTFTDFSITTNWQLHVEDIYARLFTNHNK 252

  Fly   205 SLAMEKLRVPPLGEPTPPSMVFRAGIALGMLIMLLVATAISYWKRAPLEDHTPGLMRLFRGPFTW 269
            .||:|.|:.....|....:.: |.|:..|..:.|.:..|..|    ...:.:..|:::: |.|..
pombe   253 KLALEHLKSFRQKEHFSANSM-RFGLLFGAGLPLAIEAACYY----NATEQSSYLLQIW-GGFFL 311

  Fly   270 VIFNFYM-AANVAGWQQAGVNHILIFEIDPRSHLQPATFLEIA----CTFGILWALSMLGFLYND 329
            |||.|.: ..:...|::..||::||||.:.|..|.....|||.    ..|.:.:.|.|..|....
pombe   312 VIFAFVLFDLDCYVWEKTRVNYMLIFEFNQRKSLNWRQHLEIVGAVFFIFSLFFFLCMRNFFPGF 376

  Fly   330 LIGVSDPYVFPLGLILIMVG-LLVVPLPIMNWPARWWTIKLVGRVITAPLHYVGFADFWMGDQMN 393
            .|      .|| .|.|.:|| .|:.|:.:..|..|.:.|..:.||..:.|..|.|.||:..|||.
pombe   377 TI------YFP-ALFLGVVGTFLIAPVIVPYWRMRRYLIIQLIRVFLSGLSTVHFQDFFFADQMV 434

  Fly   394 SLVSCIVDHYYTVRFYAISWLRYDRVNNCFEPDVMVPITMCLPGWFRFAQCLRRFRDSGSKSMSY 458
            ||.....:.......|...|.:....|:...|  ::.....|||..|..||.||:.|| .||..:
pombe   435 SLTYACGNISLFFCLYKRLWRQPQLCNSSHSP--LLGFFTTLPGILRVFQCFRRYSDS-LKSFPH 496

  Fly   459 LINAGKYSTTFLVVLFSTLRRNSEGGYANTFSNPYTWLFLSSCVVATIYCYLWDVIRDFGLFRIM 523
            |:||.||....|..:|.:|.|...|       ..|..|:.....|.:::.|.||::.|:.|. :.
pombe   497 LVNALKYIFNILAQMFLSLWRIHPG-------LKYRVLYTIFAGVNSLFSYTWDILMDWNLL-VR 553

  Fly   524 RGERIFLRKQLVYPQAFYYFV-IVENLVLRLFWAVEFTILYHNLMTPYNMRTISSILEITRRFIW 587
            :..|...|:..:..|.:.|.: ::.|.::|..: :.:.|..:::.....:....::.||.||.:|
pombe   554 KDGRWQFREHRILKQLWPYIIAMILNFIVRSSF-IFYCIFPNHIQHSSGISFFVTLAEIMRRCMW 617

  Fly   588 NYVRLENEHLFNCGNFRATRDIH-LAALNPRQERML--------------ESMMDESD 630
            |.:|:|:|.::|..|.||.|::. |..:.|..:..:              :||.|::|
pombe   618 NILRVEHEEIYNRENLRAARELKPLDFVKPHSDVFVSHQISSDKNYTDDEDSMDDQTD 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2901	NP_570077.1	SPX_XPR1_like	2..158	CDD:269898	53/211 (25%)
		EXS	259..597	CDD:460816	97/344 (28%)
spx2	NP_588554.2	COG5408	1..272	CDD:227695	72/278 (26%)
		COG5409	271..641	CDD:227696	108/394 (27%)