Protein Alignment CG2901 and Xpr1

DIOPT Version :10

• Sequence 1: NP_570077.1
• Gene: CG2901 / 31338
• FlyBaseID: FBgn0029679
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001099462.1
• Gene: Xpr1 / 289424
• RGDID: 1306554
• Length: 696
• Species: Rattus norvegicus
• Alignment Length: 690
• Identity: 273/690 - (39%)
• Similarity: 396/690 - (57%)
• Gaps: 67/690 - (9%)

  Fly     1 MKFGKTYESHLTIEWRQQYMRYGDLKELIKQGVENAPSPLTSSDYEVQAYYKAFEETFLTECQSE 65
            |||.:...:|:|.|||:||::|...|:::....:.|||...:.:..|:.|:..|||.|...|:.|
  Rat     1 MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKE 65

  Fly    66 LTGVNNFFLEKLLEARRKHGHLKLQLLAYSREPGHTGSDSSLSQR---------AERSQKKLMTT 121
            |..:|.|:.|||.||:|:...|:.:|.:.......:...::|.||         .||.|.:  ..
  Rat    66 LAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHR--NI 128

  Fly   122 RQLRYAYAEFYLSLVLIQNYQSLNETGFRKICKKYDKNMRSVAAGRWFVENVLDAPFTDVRLLQR 186
            :.|:.|::||||||:|:||||:||.||||||.||:||.:.:.....|.|.:|..|||...:.:.:
  Rat   129 KDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHVEVAPFYICKKINQ 193

  Fly   187 MTIEVEDLYTTHLANGDRSLAMEKLRVPPLG--EPTPPSMVFRAGIALGMLIML---LVATAI-- 244
            :..|.|.:.|..|.:|||..||::|||||||  :|.|....||.|:..|:.|:|   ||..|:
  Rat   194 LISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLFFGIFIVLNITLVFAAVFK 258

  Fly   245 -----SYWKRAPLEDHTPGLMRLFRGPFTWVIFNFYMAANVAGWQQAGVNHILIFEIDPRSHLQP 304
                 :.|.          |:|::||.|..:.|.|.:..|..||:||||||:||||::||::|..
  Rat   259 LETDRTVWP----------LIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRNNLSH 313

  Fly   305 ATFLEIACTFGILWALSMLGFLYNDLIGVSDPYVFPLGLILIMVGLLVVPLPIMNWPARWWTIKL 369
            ....|||...||||.||:|...:.. |.:...||:||.|...||..|:.|.....:.:|:|.:||
  Rat   314 QHLFEIAGFLGILWCLSLLACFFAP-ISIIPIYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKL 377

  Fly   370 VGRVITAPLHYVGFADFWMGDQMNSLVSCIVDHYYTVRFYAISWLRYDRVNNCFEPDVMVP---- 430
            :.||.|||.|.|||||||:.||:|||...::|..|.:.||:.. |::|........|...|
  Rat   378 LFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSFE-LKWDESKGLLPNDPQEPEFCH 441

  Fly   431 --------ITMCLPGWFRFAQCLRRFRDSGSKSMSYLINAGKYSTTFLVVLFSTL-RRNSEGGYA 486
                    |..|:|.|.||.|||||:||: .::..:|:|||||||||..|.|:.| ..:.|.|::
  Rat   442 GYTYGVRAIVQCIPAWLRFIQCLRRYRDT-RRAFPHLVNAGKYSTTFFTVTFAALYSTHKERGHS 505

  Fly   487 NTFSNPYTWLFLSSCVVATIYCYLWDVIRDFGLFRIMRGERIFLRKQLVYPQ-AFYYFVIVENLV 550
            :|....|.|:..  |::::.|..:||:..|:|||....||..|||:::|||| |:||..|||:::
  Rat   506 DTMVFFYLWVVF--CIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYYCAIVEDVI 568

  Fly   551 LRLFWAVEFTILYHNLMTPYN------MRTISSILEITRRFIWNYVRLENEHLFNCGNFRATRDI 609
            ||..|.::.:|    ..|.:.      :.|:.:.||:.|||:||:.|||||||.|||.|||.|||
  Rat   569 LRFAWTIQISI----TATTFKPHVGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDI 629

  Fly   610 HLAALNPRQERMLESMMDESDGVSNRRKS-----NERIRL 644
            .:|.||...:.:||.|||:.|||.||:||     |:.|.|
  Rat   630 SVAPLNADDQTLLEQMMDQEDGVRNRQKSRSWKYNQSISL 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2901	NP_570077.1	SPX_XPR1_like	2..158	CDD:269898	62/164 (38%)
		EXS	259..597	CDD:460816	145/357 (41%)
Xpr1	NP_001099462.1	SPX_XPR1_like	2..165	CDD:269898	62/164 (38%)
		EXS	268..617	CDD:460816	145/357 (41%)