Protein Alignment Mnt and Myc

DIOPT Version :10

• Sequence 1: NP_570071.3
• Gene: Mnt / 31331
• FlyBaseID: FBgn0023215
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: NP_036735.2
• Gene: Myc / 24577
• RGDID: 3130
• Length: 453
• Species: Rattus norvegicus
• Alignment Length: 486
• Identity: 95/486 - (19%)
• Similarity: 168/486 - (34%)
• Gaps: 127/486 - (26%)

  Fly    75 IIATPPFTNGNGNGTVGVGNASAIFNVSVNANGNGLSNGHSSPRSQLAAAATAHDYEYSAAGVAN 139
            ::.|||.:....:|.......:...:.|...:.:| ..|:.|...||.....          :..
  Rat    69 LLPTPPLSPSRRSGLCSPSYVAVATSFSPREDDDG-GGGNFSTADQLEMMTE----------LLG 122

  Fly   140 GHSEGRPHVSEDDNSSINNNNNNNNTHPPQQQQHSAAGRTTTTRITTTPAILTKLMGNSVTPASN 204
            |....:..:.:.|:.:...|....:.   .....|||.:..:.::.:..|  .:....|::||..
  Rat   123 GDMVNQSFICDPDDETFIKNIIIQDC---MWSGFSAAAKLVSEKLASYQA--ARKDSTSLSPARG 182

  Fly   205 TTSLPTST---------------PSVTTSPPASTDFMLLAAAATSATSATPATATSAAATAASNP 254
            .:...||:               |||....|.:             .|::|.:.||:.:||.|:.
  Rat   183 HSVCSTSSLYLQDLTAAASECIDPSVVFPYPLN-------------DSSSPKSCTSSDSTAFSSS 234

  Fly   255 AKRKLSSIAE---IPSKFLVVSDAKGVYSAHTHPNGFAADSLGVDNNETMIKKLMQNLQSQRQQQ 316
            :...|||.:.   .|...::..:.         |...::||....::|..|     ::.|..::|
  Rat   235 SDSLLSSESSPRATPEPLVLHEET---------PPTTSSDSEEEQDDEEEI-----DVVSVEKRQ 285

  Fly   317 SLQQLRSLRPAEISLTPPPAATRKVDISNSRTRSYSLSNVSAARDQQDHPQHQQHANHMQIQQH- 380
                             |||           .||.|.|:.|....:..|........|:...||
  Rat   286 -----------------PPA-----------KRSESGSSPSRGHSKPPHSPLVLKRCHVSTHQHN 322

  Fly   381 YGYMRSNIGGVIYGLHKDSADSAASSACGAGAGAAAVGMSIASSAPAAGSQLSAHHHTGHGGRRR 445
            |....|.        .|| ..:|..:...:|.....:..:...|:|.:..       |....:||
  Rat   323 YAAPPST--------RKD-YPAAKRAKLDSGRVLKQISNNRKCSSPRSSD-------TEENDKRR 371

  Fly   446 TTSSNSNGAGTREVHNKLEKERRAQLKECYDLLKKVLPMGDEDRKKTSNLTILDTAHKYVNSLSH 510
            |             ||.||::||.:||..:..|:..:| ..|:.:|...:.||..|..|:.|:
  Rat   372 T-------------HNVLERQRRNELKRSFFALRDQIP-ELENNEKAPKVVILKKATAYILSV-- 420

  Fly   511 EVCEQEAKIEKLAKQKIELQKRLKQLSLRRE 541
                 :|...||..:|..|:||.:||..:.|
  Rat   421 -----QADEHKLISEKDLLRKRREQLKHKLE 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mnt	NP_570071.3	bHLHzip_Mnt	455..533	CDD:381408	23/77 (30%)
Myc	NP_036735.2	Myc_N	16..359	CDD:460045	63/369 (17%)
		9aaTAD. /evidence=ECO:0000250|UniProtKB:P01106	115..123		0/17 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..373		42/227 (19%)
		bHLHzip_c-Myc	365..448	CDD:381464	30/103 (29%)
		UBR5-degron. /evidence=ECO:0000250|UniProtKB:P01106	369..378		6/21 (29%)
		Leucine-zipper	427..448		8/20 (40%)