Protein Alignment Myc and mycn

DIOPT Version :10

• Sequence 1: NP_525062.2
• Gene: Myc / 31310
• FlyBaseID: FBgn0262656
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001006874.1
• Gene: mycn / 448649
• XenbaseID: XB-GENE-478859
• Length: 445
• Species: Xenopus tropicalis
• Alignment Length: 273
• Identity: 62/273 - (22%)
• Similarity: 114/273 - (41%)
• Gaps: 47/273 - (17%)

  Fly   457 FNLPYTPASS---SPVKSVANSRYPSPSSTP---------------YQNCSSASPSYSPLSVDSS 503
            |..|:....|   :|..|.|:|..|.|.:|.               ..:|||...|:|....|..
 Frog   179 FPFPFNKGESCRTAPAGSAASSANPPPCTTTSVPAAATARSCTQPCSTSCSSGEESHSDSDDDEE 243

  Fly   504 NVSSSSSSSSSQSSFTTSSSNKGRKRSSLKDPGLLISSSSVYLPGVNNKVTHSSMMSKKSRGKKV 568
            ...........:.......:.:.|:.||.|.    ::|.::.:     :..::.::|.|:...:|
 Frog   244 EEEEEEEEEDDEEEEIDVVTVEKRRNSSNKS----VTSLTITV-----RPKNTILVSAKTTQNEV 299

  Fly   569 V---------GTSSGNTSPISSGQDVDAMDRNWQRRSGGIATS---TSSNSSVHRKDFVLGFDEA 621
            :         ..:....||....::|....:..:.....:..|   |.:.||..|     .:|..
 Frog   300 ILKRCAPVHQQHNYAAPSPYVETEEVAPPQKKQKNELPRLVKSVVPTKAKSSSPR-----NYDSE 359

  Fly   622 DTIEKRNQHNDMERQRRIGLKNLFEALKKQIPTIRDKERAPKVNILREAAKLCIQLTQEEKELSM 686
            |: |:|..||.:|||||..|::.|..|:..:|.:...|:|.||.||::|.:....|..:|::|.:
 Frog   360 DS-ERRRNHNILERQRRNDLRSSFLTLRDHVPELIKNEKAAKVVILKKATEYVHSLHADEQKLLL 423

  Fly   687 QRQLLSLQLKQRQ 699
            :::  .|||:|:|
 Frog   424 EKE--KLQLRQQQ 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myc	NP_525062.2	bHLHzip_Myc	626..702	CDD:381406	27/74 (36%)
mycn	NP_001006874.1	Myc_N	2..353	CDD:460045	31/182 (17%)
		bHLHzip_N-Myc_like	359..445	CDD:381462	29/79 (37%)