Protein Alignment Syx4 and Stx19

DIOPT Version :10

• Sequence 1: NP_525057.2
• Gene: Syx4 / 31269
• FlyBaseID: FBgn0024980
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_001102930.1
• Gene: Stx19 / 685180
• RGDID: 1597703
• Length: 292
• Species: Rattus norvegicus
• Alignment Length: 317
• Identity: 64/317 - (20%)
• Similarity: 130/317 - (41%)
• Gaps: 55/317 - (17%)

  Fly     3 KDRLPELLQRSLSTNSSNSSSNGSLLLNVYSGTTEFIIGNTGGNNNSYSVVSQNSHSCSNNNSST 67
            ||||.||.|::.....|..|       .|::...:.::       ...:|:.:.
  Rat     2 KDRLQELKQKTKEIELSRDS-------QVFAEEEQGVL-------VQQAVIYER----------- 41

  Fly    68 EP-KDRSSSKMTQYGSNVDDILNPYTEIRQQLAQIAANLETMNRMAQTVNLRTFNENEMDELHNK 131
            || .:|...::.:...|::..::......||...:.|            ::|.|:..:.|....|
  Rat    42 EPVAERHLHEIHKLQENINSFVDDVHRFGQQQKSLVA------------SMRRFSLLKRDSTITK 94

  Fly   132 NLRLGNQLMTR-----FNDFKANLPAENDYSLEARMKRTLFYGLHQTFINLWHKNELFLQNYETK 191
            .::|..:.:.|     ..:.|.:.......|:..|:.::.:..:.:.|     :..|||.| :|.
  Rat    95 EIKLQAEHINRALGDVVREVKKSEVENGPSSVITRILKSQYAAMFRRF-----QQTLFLYN-DTI 153

  Fly   192 VKKNLRLHTKII------NSEASEQEIELLIENKTTKLFVDNFLQETEKERQTLREMMDRFNELR 250
            ..|..:..|.|:      ..|.||:|:..::.:...::|.::.|.||...:..|.|:..|..||.
  Rat   154 ALKQEKCKTFIVRQLEVSGKEVSEEEVNDMLHHGKWEVFNESLLTETSMTKAQLSEIEQRHKELV 218

  Fly   251 RLEKSIEEVHALFMRIQTLVMEQSEVIQRVEFHAQQATLHVDKGADELDQAEQHQKK 307
            .||..::::..||::|..||.||.|.|..:|........:|:...::...|.::::|
  Rat   219 NLENQVKDLRDLFIQISLLVEEQGESINNIEVMVNSTKDYVNNTKEKFGLAVKYKRK 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx4	NP_525057.2	COG5074	<187..313	CDD:227406	33/127 (26%)
		SNARE_syntaxin1-like	238..298	CDD:277201	18/59 (31%)
Stx19	NP_001102930.1	Syntaxin	47..242	CDD:459942	44/212 (21%)
		SNARE	210..276	CDD:473982	18/66 (27%)