Protein Alignment Syx4 and stx12

DIOPT Version :10

• Sequence 1: NP_525057.2
• Gene: Syx4 / 31269
• FlyBaseID: FBgn0024980
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: XP_009292403.1
• Gene: stx12 / 415141
• ZFINID: ZDB-GENE-040625-11
• Length: 267
• Species: Danio rerio
• Alignment Length: 291
• Identity: 68/291 - (23%)
• Similarity: 138/291 - (47%)
• Gaps: 46/291 - (15%)

  Fly    59 SCSNNNSSTEPKDRSSSKMTQYGSNVDDILNPYTEIRQQLAQIAANLETMNRMAQTVNLRTFNEN 123
            |....:....|||.||...| ..||:..|.....:|:..:.|:...|:| :.:.:.:.....:.|
Zfish     2 SYGRTDQRASPKDFSSLIQT-CSSNIQKITLNTAQIKGLVNQLGTKLDT-SGLRERLQYMQHHTN 64

  Fly   124 EMDELHNKNLR-LGNQLMTRFNDFKANLPAENDYSLEARMKRTLFYGLHQTFINLWHKNELFLQN 187
            ::.:..||:|: ||:          .:||.......:.::::.          .|.:.....|.|
Zfish    65 QLAKETNKHLKDLGS----------ISLPVSLSEQRQQKIQKD----------RLMNDFSAALNN 109

  Fly   188 YET-------KVKKNL---RLHTKIINSEASEQEIELLIEN-----KTTKLFVDNFLQETEKERQ 237
            ::.       |.|:::   |..:::...:....|..:..:|     |||....|  :..||::.:
Zfish   110 FQAVQRQAAEKEKESVARARAGSRLSADDGGHDEQLVSFDNNDDWGKTTTQTED--VAITEEDLE 172

  Fly   238 TLREMMDRFNELRRLEKSIEEVHALFMRIQTLVMEQSEVIQRVEFHAQQATLHVDKGADELDQAE 302
            .::|   |...:|:||..|.:|:.:|..:..::.:|.|:|..:|.:.:.|.:||::||::|.:|.
Zfish   173 LIKE---RETAIRQLESDILDVNQIFKDLAVMIHDQGEMIDSIEANVESAEVHVERGAEQLQRAA 234

  Fly   303 QHQKKARKKKIMLIVILAAVLLVLLLVGIYL 333
            |:|:|:|||...|.|.|:   :|:|::||.:
Zfish   235 QYQQKSRKKICFLAVGLS---IVVLIIGIVI 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx4	NP_525057.2	COG5074	<187..313	CDD:227406	37/140 (26%)
		SNARE_syntaxin1-like	238..298	CDD:277201	17/59 (29%)
stx12	XP_009292403.1	Syntaxin_2	23..125	CDD:464199	20/122 (16%)
		SNARE_syntaxin12	174..240	CDD:277229	21/68 (31%)