Protein Alignment Syx4 and Stx2

DIOPT Version :10

• Sequence 1: NP_525057.2
• Gene: Syx4 / 31269
• FlyBaseID: FBgn0024980
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: XP_063127147.1
• Gene: Stx2 / 25130
• RGDID: 2558
• Length: 297
• Species: Rattus norvegicus
• Alignment Length: 263
• Identity: 57/263 - (21%)
• Similarity: 133/263 - (50%)
• Gaps: 28/263 - (10%)

  Fly    71 DRSSSKMTQYGSN-----------VDDILNPYTEIRQQLAQIAANLETMNRMAQTVNLRTFN--- 121
            |.::.:.:..|.|           :|...:...|||..:|:||.::|.:.: ..::.|...|
  Rat     7 DLTACRKSDDGDNAVIITVEKDHFMDAFFHQVEEIRSSIARIAQHVEDVKK-NHSIILSAPNPEG 70

  Fly   122 --ENEMDELHNKNLRLGNQLMTRFNDFKANLPAE---NDYSLEARMKRTLFYGLHQTFINLWHK- 180
              :.|:::|:.:..:..|::..:....:.:...:   |..|::.|::||....|.:.|:::..:
  Rat    71 KIKEELEDLNKEIKKTANRIRGKLKAIEQSCDQDENGNRTSVDLRIRRTQHSVLSRKFVDVMTEY 135

  Fly   181 NE---LFLQNYETKVKKNLRLHTKIINSEASEQEIELLIENKTTKLFVDNFLQETEKERQTLREM 242
            ||   ||.:..:.::::.|    :|.....:::|:|.::|:....:|:.:.:.:::..||.|.|:
  Rat   136 NEAQILFRERSKGRIQRQL----EITGRTTTDEELEEMLESGKPSIFISDIISDSQITRQALNEI 196

  Fly   243 MDRFNELRRLEKSIEEVHALFMRIQTLVMEQSEVIQRVEFHAQQATLHVDKGADELDQAEQHQKK 307
            ..|..::.:||.||.|:|.:||.:...|..|.|::..:|.:...:..:|:...:|..:|.::|.|
  Rat   197 ESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMVNNIERNVVNSVDYVEHAKEETKKAIKYQSK 261

  Fly   308 ARK 310
            ||:
  Rat   262 ARR 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx4	NP_525057.2	COG5074	<187..313	CDD:227406	30/124 (24%)
		SNARE_syntaxin1-like	238..298	CDD:277201	16/59 (27%)
Stx2	XP_063127147.1	None