Protein Alignment fs(1)Yb and PRP5

DIOPT Version :10

• Sequence 1: NP_477494.2
• Gene: fs(1)Yb / 31262
• FlyBaseID: FBgn0000928
• Length: 1042
• Species: Drosophila melanogaster
• Sequence 2: NP_009796.1
• Gene: PRP5 / 852539
• SGDID: S000000441
• Length: 849
• Species: Saccharomyces cerevisiae
• Alignment Length: 642
• Identity: 119/642 - (18%)
• Similarity: 225/642 - (35%)
• Gaps: 205/642 - (31%)

  Fly   136 LSISARNAEMLVITPCDEENEKEGKGETEPEIVQQRMPLKVDALNSMQLYEIKENTPPTSSEDYK 200
            :.:|.|:.|.:...| :.:|||:...|....:.:::|.      ||..:|:
Yeast   115 IGVSFRSKEHIQKAP-EHDNEKDPLDEFMTSLKEEKMS------NSKGMYD-------------- 158

  Fly   201 AEADVLLSAATPATIPNDNKEQEINLSVEDATVKLLASFELGSTDSAAVDESSPAA-----AKFN 260
             ..|:                    |.|||..      ||||.||...|::::..:     ||..
Yeast   159 -RGDI--------------------LDVEDQL------FELGGTDDEDVEDNTDNSNIAKIAKLK 196

  Fly   261 AP------VYSPFVTENPTKSLDAEFQELVKSFKVQNVFKNMNLPPPPSVSIEEPVSSASASDYR 319
            |.      .|||           .|.:...|:|.:::                |.|||.|..:..
Yeast   197 AKKRVKQIYYSP-----------EELEPFQKNFYIES----------------ETVSSMSEMEVE 234

  Fly   320 HQIDTTSLDSIRTVKDSPASLAVVPFSAGGITYNNYGVLGWSRH--AVVPCYGLTEAPDISTIIR 382
            ..  ..|||:|: :|.:.....|..:|..|::.:...::....|  ::.|
Yeast   235 EL--RLSLDNIK-IKGTGCPKPVTKWSQLGLSTDTMVLITEKLHFGSLTP--------------- 281

  Fly   383 RAMQQMGVARSRARAVQRFAWPHVSLGKSVLVVGNLQIGKTWSY-LPTVCQ-RSHEDLQRRPDVG 445
                           :|..|.|.:..|:.|:.:.....|||.|| ||.:.| ::...|.:..
Yeast   282 ---------------IQSQALPAIMSGRDVIGISKTGSGKTISYLLPLLRQVKAQRPLSKHE--- 328

  Fly   446 RGPTCIFVCPNQGQGKQIERWMS----------TLLCLLGSASGFEDVVTHWDKTQLVDIVRRLK 500
            .||..:.:.|.:....||...::          ::.|..||..          |.|:.|    ||
Yeast   329 TGPMGLILAPTRELALQIHEEVTKFTEADTSIRSVCCTGGSEM----------KKQITD----LK 379

  Fly   501 KPVGILLTSVDLLLQLLNHNPVGSIFDAQAVKCIALDNLNDM--VRVLPNDTMKLLQRLPE---- 559
            :...|::.:....:.:|..|. |.:...:.:..:.:|..:.:  :...|..|..:....|:
Yeast   380 RGTEIVVATPGRFIDILTLND-GKLLSTKRITFVVMDEADRLFDLGFEPQITQIMKTVRPDKQCV 443

  Fly   560 MFQLT-QNKCQLLVSGRIWHTDLMVQHILPLMPDVLVLFDDALEASVYGGVQLDVRVVADEPEKI 623
            :|..| .||.:.. :.|:.|:.:.:              ....:..|...|:...|:...|.||.
Yeast   444 LFSATFPNKLRSF-AVRVLHSPISI--------------TINSKGMVNENVKQKFRICHSEDEKF 493

  Fly   624 EHLKALIAERRNFANE-----------------PAVMVCSNSTEVLLLRRSLQAIGVNAHICVSE 671
            ::|..||.||..|.:|                 .|::..|:......:.:.|...|:     |:.
Yeast   494 DNLVQLIHERSEFFDEVQSENDGQSSDVEEVDAKAIIFVSSQNICDFISKKLLNAGI-----VTC 553

  Fly   672 ACYS---------NVAEWLRQSPSGLLLVTDDVVPRLKCGKIPLLIHYSFASMWARF 719
            |.::         |:.::.|:..| :||.|:.:...|...::.|:|.|:....:|::
Yeast   554 AIHAGKPYQERLMNLEKFKREKNS-ILLCTEVLSRGLNVPEVSLVIIYNAVKTFAQY 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)Yb	NP_477494.2	Tudor_SF	<862..960	CDD:470623
PRP5	NP_009796.1	DEADc_DDX46	244..468	CDD:350711	47/287 (16%)
		SrmB	255..707	CDD:440279	75/424 (18%)
		KH-I_PRP5_like	749..837	CDD:411902