Protein Alignment fs(1)Yb and Tdrd12

DIOPT Version :10

• Sequence 1: NP_477494.2
• Gene: fs(1)Yb / 31262
• FlyBaseID: FBgn0000928
• Length: 1042
• Species: Drosophila melanogaster
• Sequence 2: XP_063134069.1
• Gene: Tdrd12 / 689639
• RGDID: 1562792
• Length: 1333
• Species: Rattus norvegicus
• Alignment Length: 973
• Identity: 196/973 - (20%)
• Similarity: 346/973 - (35%)
• Gaps: 284/973 - (29%)

  Fly   165 PEIVQ----QRMPLKVDALNSMQLYEIKENTPPTSSEDYKAE----ADVLLSAAT-------PAT 214
            |.::|    |||.      ||..|..:.::...|..:|...:    |.||..|..       ..|
  Rat   245 PMLLQGKDCQRME------NSQSLDFLAQSLQHTWCKDVVGDLGPRAAVLDKAVNYKDSLTDSPT 303

  Fly   215 IPNDNKEQEINLSVEDATVKLLASFELGSTDSAAVDESSPAAAKFNAPVYSPFVTENP---TKSL 276
            |..:.|:|.:.|...|..::....:......:...|...|||:     |:|...:|.|   |:..
  Rat   304 IMFEKKQQSLPLKHMDKCIESSMYWPTKRGITIYADPDIPAAS-----VFSQKPSEKPLRLTEKK 363

  Fly   277 DA-EFQELVKSFKVQNVFKNMNLPPPPSVSIEEPVSSASASDYRHQIDTTSLDSIRTVKDSPASL 340
            |. |....||..:..|               .:|:.:...||. ||:....|.:::.
  Rat   364 DCDEKNGCVKLLQFLN---------------PDPLRADEISDL-HQLQKVKLGTLQP-------- 404

  Fly   341 AVVPFSAGGITYNNYGVLGWSRHAVVPCYGLTEAPDISTIIRRAM---------QQMGVARSR-- 394
                           ||:  .|:.:.||..|.::| :|..:::.|         :.|.||...
  Rat   405 ---------------GVV--LRNRIEPCLTLDKSP-LSADLKKHMALTRLNSDIEVMKVAMEEVI 451

  Fly   395 -ARAVQR-----------FAWPHVSLGKSVLVV---GN------------LQIGKTWSYLPTVCQ 432
             |.|:||           ::||.::.|..|:|:   ||            ||:|..:..||:
  Rat   452 PAEALQRNKFPGPSHTASYSWPPIARGCDVVVISHCGNDPLLYLPPLLTILQMGGCYKSLPS--- 513

  Fly   433 RSHEDLQRRPDVGRGPTCIFVCPN----------QGQGKQIERWMSTLLCLLGSASGFEDVVTHW 487
                        ..||..:.|||.          .|......|.:..:|..:|         .|.
  Rat   514 ------------RNGPLAVIVCPGWKKAQFIFELLGDYSMSSRPLHPVLLTIG---------LHK 557

  Fly   488 DKTQLVDIVRRLKKPVG--ILLTSVDLLLQLLNHNPVGSI--------------FDAQAVKCIAL 536
            |:      .:.:|.|.|  :::|:...||:||.:..:..:              |:|.......|
  Rat   558 DE------AKNMKLPRGCDVIVTTPHSLLRLLTYRSLLFLRLCHLVLDEVHVLFFEANEQMFAIL 616

  Fly   537 DNLNDMVRVLPNDTMKLLQRLPEMFQLTQNKCQLLVSGRIWHTDLMVQHIL-PLMPDVLVLFDDA 600
            ||....|.|...::      .|.         |::..|..|:..  ::|:: ..|.|..|:....
  Rat   617 DNFKKNVEVEERES------APH---------QIVAVGVHWNRH--IEHLVREFMKDPHVVITAL 664

  Fly   601 LEASVYGGVQLDVRVVADEPEKIEHLKALIAERRNFANEPAVMVCS-NSTEVLLLRRSLQAIGVN 664
            .||::||.||..|.:.. |.||...|..::....:.|.:..:..|| ..||::     .:.:..|
  Rat   665 EEAALYGSVQQVVHLCL-ECEKTSTLLQVLDFVPSQAQKTLIFTCSVAETEIV-----CKVVESN 723

  Fly   665 AHICV---SEACY---SNVAEWLRQSPSG---LLLVTDDVVPRLKCGKIPLLIHYSFASMWARFK 720
            :..|:   .|..:   |.:.:|.::..||   :|.:|||.:|.|.......::|:||.|....|.
  Rat   724 SIFCLKMHKEMAFNLKSILEQWKKKLSSGSHIVLTLTDDCIPLLAITDATCVVHFSFPSSPKVFG 788

  Fly   721 NRFSLFYANLKSPTTR--PVGQ------SVVFAKPTDLENIWKLCDFYMKHKLPRPGHL----LG 773
            .|......:.:|.|.:  |..|      ||:.....:..:...:..:..:.....|..|    .|
  Rat   789 GRLYCMSDHFQSLTEQGSPAEQGGKKTKSVLLLTERNASHAVGVLRYLERADAKIPSELYEFTAG 853

  Fly   774 ILSQRRLEEQPTSRSLCHQMAAFGDCLRHKCMYRHVMWRDEVLPPDHY---PKNGLIRFLVLVCY 835
            :|..:  |::...|.||..:.|||.|            :|:.:.||.:   |:..:.|
  Rat   854 VLEAK--EDKKARRPLCPYLKAFGFC------------KDKRICPDRHHINPEMDIPR------- 897

  Fly   836 SPAALAVRLSDQ-FPT--AIRFLNFPMSD----LGERVQRHYEL------EANRHMH--PNPVPG 885
                   :||:: .|.  .||.:.|.:|:    .|..:.:|.:|      |.|.:..  .|....
  Rat   898 -------KLSNETLPVFGHIRIIPFYISNATNYFGRIIDKHVDLYETLNAEMNEYFKDPSNKTAA 955

  Fly   886 EMAVVKNINRY--------ERVHIVSVESNV------MVLVQLLDTS-TECFSYKTSQLYSCDKI 935
            |.  |:|:..|        :||.::......      .|||:.:|.. |:..:  ..||....:.
  Rat   956 EK--VENLGLYGLEEKTLFQRVQVLEASQKEDTWGLGSVLVKFIDEGRTKLIT--RDQLLLLPEK 1016

  Fly   936 FKDSPREAMDLRILGLQPESLDRIWPDDARNLVRKDFFRRTHNKRNRQFHAVVQSAIHRTIFV 998
            |...|.:|::..:..::|...:..|.......:......:.|       .|.|..|:..|:::
  Rat  1017 FHTLPPQAVEFIVCRVKPADSEIEWNPKVTRYIHHKIIGKMH-------EAKVVFALGNTLWI 1072

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fs(1)Yb	NP_477494.2	Tudor_SF	<862..960	CDD:470623	23/120 (19%)
Tdrd12	XP_063134069.1	None