Protein Alignment Raf and Tak1

DIOPT Version :10

• Sequence 1: NP_525047.1
• Gene: Raf / 31221
• FlyBaseID: FBgn0003079
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_524080.1
• Gene: Tak1 / 39659
• FlyBaseID: FBgn0026323
• Length: 678
• Species: Drosophila melanogaster
• Alignment Length: 332
• Identity: 90/332 - (27%)
• Similarity: 158/332 - (47%)
• Gaps: 51/332 - (15%)

  Fly   428 EILIGPRIGSGSFGTVYRAHWHGP-VAVKTLNVKTPSPAQLQAFKNEVAMLKKTRHCNILLFMGC 491
            ||.:..::|.||:|.|.:|.|... ||||...    :.|:.:..:.||..|.:.:|.||:...|.
  Fly    18 EITLREKVGHGSYGVVCKAVWRDKLVAVKEFF----ASAEQKDIEKEVKQLSRVKHPNIIALHGI 78

  Fly   492 VS-KPSLAIVTQWCEGSSLYKHVHVS-ETKFKLNTLIDIGRQVAQGMDYLHA---KNIIHRDLKS 551
            .| :.:..::.::.||.||:..:|.. :..:.|...:...||.|:|:.||||   |.:||||:|.
  Fly    79 SSYQQATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMTPKPLIHRDVKP 143

  Fly   552 NNIFL-HEDLSVKIGDFGLATAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFG 615
            .|:.| ::..::||.|||....|:......:     ||..||||||.   |.:.|:.:.|::::.
  Fly   144 LNLLLTNKGRNLKICDFGTVADKSTMMTNNR-----GSAAWMAPEVF---EGSKYTEKCDIFSWA 200

  Fly   616 IVMYELLAECLPYGHISNKDQILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFR 680
            ||::|:|:...|:..|.|...|.:.:.:|...|    :.:..|:.::.|...|.|..|:|||..:
  Fly   201 IVLWEVLSRKQPFKGIDNAYTIQWKIYKGERPP----LLTTCPKRIEDLMTACWKTVPEDRPSMQ 261

  Fly   681 PLLNMLENMLRTLPKIHRS-------------------ASEPNLTQSQLQNDEFLYLPS-----P 721
            .::.::..:::......::                   |::|:...||    |....||     |
  Fly   262 YIVGVMHEIVKDYTGADKALEYTFVNQQIVTKESDGTVAAQPDSLSSQ----EGELSPSSTQLTP 322

  Fly   722 KTPVNFN 728
            .|..|.|
  Fly   323 TTAANAN 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Raf	NP_525047.1	RBD_RAF	142..212	CDD:340514
		C1_Raf	221..269	CDD:410361
		STKc_Raf	435..687	CDD:270964	77/258 (30%)
Tak1	NP_524080.1	STKc_TAK1	25..275	CDD:270960	77/265 (29%)