Protein Alignment CG3078 and UNC93B1

DIOPT Version :10

• Sequence 1: NP_001356930.1
• Gene: CG3078 / 31211
• FlyBaseID: FBgn0023524
• Length: 765
• Species: Drosophila melanogaster
• Sequence 2: NP_112192.2
• Gene: UNC93B1 / 81622
• HGNCID: 13481
• Length: 597
• Species: Homo sapiens
• Alignment Length: 521
• Identity: 107/521 - (20%)
• Similarity: 189/521 - (36%)
• Gaps: 120/521 - (23%)

  Fly   257 LAHGLMNCVLLPVMALQGSNAVWHHREEWLPLG------PEVGSLLLSALFLVAAGMSLPSIRLM 315
            |.:|    |.|.::.:|   .:.|:.|.:..:.      |::.|.:|       .|:::..|..:
Human    73 LTYG----VYLGLLQMQ---LILHYDETYREVKYGNMGLPDIDSKML-------MGINVTPIAAL 123

  Fly   316 KRYGYGPLIVANYMTV-LLFLLSHLYA---------SIYTLLPAYLLLGMTLSGSAGSKAALIVH 370
            .   |.|:::..:.|. ::||...:||         ..|||:|:.:.|||.:.....|....|..
Human   124 L---YTPVLIRFFGTKWMMFLAVGIYALFVSTNYWERYYTLVPSAVALGMAIVPLWASMGNYITR 185

  Fly   371 FGGKLSCSCDSQQSQAAVDVLHEEHKMFCNRDQKVRRLARWFRVSQDLGLIGGALLASILLACSD 435
            ...|                 :.|:..:..:|      .:..:.....|.....||....:..|.
Human   186 MAQK-----------------YHEYSHYKEQD------GQGMKQRPPRGSHAPYLLVFQAIFYSF 227

  Fly   436 GNFTGDCSGL--VYYGNESWPPQLRDFYNRNEHGDRICGADMCPLRVQSILEAGWANGSSIPSSI 498
            .:.:..|:.|  :|:.|.    .|.|. |...:..:.||                .|...|.|..
Human   228 FHLSFACAQLPMIYFLNH----YLYDL-NHTLYNVQSCG----------------TNSHGILSGF 271

  Fly   499 YAGFIESEPRVAGQSLLWLYVLFSMVSLTLSLLIVVDKVQAIGSSRPERSRDV-SITDTLLFAGP 562
            ....:.:.|| :|..::...||  |....|::|:|:....|  :.||....|: |:....:|..|
Human   272 NKTVLRTLPR-SGNLIVVESVL--MAVAFLAMLLVLGLCGA--AYRPTEEIDLRSVGWGNIFQLP 331

  Fly   563 ------------LAYFV--GTEQAYMMGDFLRAFVTCSLGIGMIAGALIGMGLMQLIVSCTLSML 613
                        :.:|:  |.|..:........:..||:|:..:|..|:...|.....| .|.:|
Human   332 FKHVRDYRLRHLVPFFIYSGFEVLFACTGIALGYGVCSVGLERLAYLLVAYSLGASAAS-LLGLL 395

  Fly   614 LRHVKRIVVILAGFFFHSCLLLALSSWKPSS---DDSALFYVIAASWGACNGMWETLLLSLVTLN 675
            ...:.|.|.::||...|..|...|..|.|..   ..|.:.||.||.||..:.:.:|.|.:|:.:.
Human   396 GLWLPRPVPLVAGAGVHLLLTFILFFWAPVPRVLQHSWILYVAAALWGVGSALNKTGLSTLLGIL 460

  Fly   676 HSSHVTE---------VQAPLLALRFLGLGLTFAGHGFLCESMKIIALVVLLVISVPPYATLEIR 731
            :.....:         .||..:...:||..|..        ..|:..|:|.||.:...|..:|.:
Human   461 YEDKERQDFIFTIYHWWQAVAIFTVYLGSSLHM--------KAKLAVLLVTLVAAAVSYLRMEQK 517

  Fly   732 L 732
            |
Human   518 L 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3078	NP_001356930.1	bZIP	<11..>43	CDD:473870
		FucP	294..>358	CDD:440501	18/73 (25%)
		MFS	<496..731	CDD:475125	60/261 (23%)
UNC93B1	NP_112192.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		MFS_unc93B1	64..520	CDD:340966	107/521 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	522..597