DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3078 and CG4928

DIOPT Version :9

Sequence 1:	NP_001356930.1	Gene:	CG3078 / 31211	FlyBaseID:	FBgn0023524	Length:	765	Species:	Drosophila melanogaster
Sequence 2:	NP_573179.1	Gene:	CG4928 / 32682	FlyBaseID:	FBgn0027556	Length:	538	Species:	Drosophila melanogaster

Alignment Length:	529	Identity:	110/529 - (20%)
Similarity:	217/529 - (41%)	Gaps:	97/529 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 AHVRQKV-------WR---QFSCLSLAHGLMNCVLLPVMALQGSNAVWHHREEWLPLGPEVGSLL 296
            |.:|:||       ||   ..|.:|:|      .::...|.||:    .:.:..:.....:|::.
  Fly    26 ASLREKVVLNPGEKWRILKNISIISIA------FMVQFTAFQGT----ANLQSSINAKDGLGTVS 80

  Fly   297 LSALF--LVAAGMSLPSIRLMKRYGYGPLIVANYMTVLLFLLSHLYASIYTLLPAYLLLGMTLSG 359
            |||::  ||.:.:.||:: ::::......:|.:.:....::...|:...|||:||.:|:||..:.
  Fly    81 LSAIYAALVVSCIFLPTL-IIRKLTVKWTLVCSMLCYAPYIAFQLFPRFYTLVPAGILVGMGAAP 144

  Fly   360 SAGSKAALIVHFGGKLSCSCDSQQSQAAVDVLHEEHKMFCNRDQKVRRLARWFRVSQDLGLIGGA 424
            ...|||..:...|     ...::.::.|||.:             :.|...:|.::.....:.|.
  Fly   145 MWASKATYLTQVG-----QVYAKITEQAVDAI-------------IVRFFGFFFLAWQSAELWGN 191

  Fly   425 LLASILLACSDGNFTGDCSGLVYYGNESWPPQLRDFYNRNEHGDRICGADMCPLRVQSILEAGWA 489
            |::|::|  |.|...|..|.......|..               :.|||:.|     :....|..
  Fly   192 LISSLVL--SSGAHGGGSSSNTTVSEEDL---------------QFCGANFC-----TTGSGGHG 234

  Fly   490 NGSSIPSSIYAGFIESEPRVAGQSLLWLYVLFSMVSLTLSLLIVVDKVQAIGSSRPERSRDVSIT 554
            |....|          |..:...|:::|..:.:.|.:   :...:|.::..|..|...:....::
  Fly   235 NLERPP----------EDEIFEISMIYLSCIVAAVCI---IAFFLDPLKRYGEKRKGSNSAAELS 286

  Fly   555 DTLLFAG--------------PLAYFVGTEQAYMMGDFLRAFVTCSLGIGMIAGALIGMGLMQLI 605
            ...|.:.              |:..|:|.|||::..||.:|:|.|:||:..|...:|..|::..:
  Fly   287 GLQLLSATFRQMKKPNLQLLIPITVFIGMEQAFIGADFTQAYVACALGVNKIGFVMICFGVVNAL 351

  Fly   606 VSCTLSMLLRHVKRIVVILAGFFFHSCLLLALSSWKPSSDDSALFYVIAASWGACNGMWETLLLS 670
            .|.....:::::.|..:|:.|...|..|:.....|:|:.|:..:||.::..||..:.:|:|.:..
  Fly   352 CSILFGSVMKYIGRTPIIVLGAVVHFTLITVELFWRPNPDNPIIFYAMSGLWGVGDAVWQTQING 416

  Fly   671 LVTLNHSSHVTEVQAPLLALRFLGLGLTFAGHGFLCESMKIIALVVLLVISVPPYATLEI----- 730
            |..|....:.....:........|..:.:|....||..||:..|:.:|.:....|..:||
  Fly   417 LYGLLFRRNKEAAFSNYRLWESAGFVIAYAYATTLCTQMKLYILLAVLTLGCIGYVIVEILYRKK 481

  Fly   731 --RLEAQRK 737
              :|:.|.|
  Fly   482 QRKLKKQEK 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3078	NP_001356930.1	bZIP	<11..>43	CDD:354818
CG3078	NP_001356930.1	MFS	<496..731	CDD:355786	52/255 (20%)
CG4928	NP_573179.1	MFS	49..>155	CDD:328737	26/116 (22%)
CG4928	NP_573179.1	MFS_1	<255..426	CDD:331686	38/173 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445364
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3097
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4703
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1145833at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19444
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.800